STE_PAK1 (Serine/threonine-protein kinase PAK 1)

Total number of chains: 69
Active chains: 10
Uniprot: PAK1_HUMAN
Kinase Domain Residues: 270 - 521
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 37 53.6% AF-Q13153-K1A
DFGout BBAminus 8 11.6% 4ZJID
DFGin BLBplus 7 10.1% 4ZY5B
DFGin None 5 7.2% 5DEYB
DFGin BLAplus 4 5.8% 9N4UB
None None 3 4.3% 5KBQB
DFGin BLBminus 2 2.9% 9D4XB
DFGin ABAminus 1 1.4% 9N48B
DFGinter None 1 1.4% 9D50B
DFGout None 1 1.4% 4ZLOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q13153-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 262 - 529 0 None None Serine/threonine-protein kinase PAK 1
AF-Q13153-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 262 - 529 0 None None Serine/threonine-protein kinase PAK 1
4ZY4A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1
4ZY5A 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T5 Type1 251 - 542 0 None None Serine/threonine-protein kinase PAK 1
4ZY6A 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T6 Type1 251 - 542 0 None D389N Serine/threonine-protein kinase PAK 1
9D4XA 1.847 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2S Type1 252 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9D50A 1.898 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2T Type1 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9D4VA 1.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2P Type1 252 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9D4YA 1.847 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2S Type1 252 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
4O0TA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OL Type1.5_Back 251 - 542 0 None None Serine/threonine-protein kinase PAK 1
9N48B 1.85 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BV1 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
4O0RB 2.4 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1
6B16A 2.285 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii C7Y Type1 251 - 542 0 None None Serine/threonine-protein kinase PAK 1
7VTOA 2.59 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 107 Type1 257 - 542 0 TPO423 None Serine/threonine-protein kinase PAK 1
5DEWA 1.9 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 59N Type1 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9D4WA 2.218 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2Q Type1 252 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
4O0RA 2.4 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 249 - 541 0 None None Serine/threonine-protein kinase PAK 1
5KBQA 2.58 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii IPV Type1 254 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1
5KBRA 2.36 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii IPW Type1 255 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1
4P90A 2.49 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 2K0 Type1 250 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1
9N48A 1.85 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BV1 Type1 249 - 545 0 None None Serine/threonine-protein kinase PAK 1
9NBXA 2.15 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW5 Type1 249 - 541 0 None None Serine/threonine-protein kinase PAK 1
5DEYA 2.1 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 59T Type1.5_Back 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
5IMEA 2.217 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6BZ Type1.5_Back 251 - 545 0 None None Serine/threonine-protein kinase PAK 1
9N4UA 1.77 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BV8 Type1.5_Back 249 - 545 0 None None Serine/threonine-protein kinase PAK 1
1F3MC 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1
1F3MD 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1
4ZY6B 2.15 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 4T6 Type1 255 - 542 0 None D389N Serine/threonine-protein kinase PAK 1
9N4UB 1.77 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno A1BV8 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
9D4XB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9D4YB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
4ZY4B 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1
4ZY5B 2.35 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T5 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
6B16B 2.285 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno C7Y Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
5DEWB 1.9 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 59N Type1 255 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9D4VB 1.84 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2P Type1 252 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9D4WB 2.218 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2Q Type1 257 - 545 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
9NBXB 2.15 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BW5 Type1 254 - 542 0 None None Serine/threonine-protein kinase PAK 1
4O0TB 2.6 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 255 - 542 0 None None Serine/threonine-protein kinase PAK 1
3Q4ZB 1.887 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 250 - 541 0 None S259I,K299R,D389N,L516I Serine/threonine-protein kinase PAK 1
7VTOB 2.59 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 107 Type1 255 - 542 0 TPO423 None Serine/threonine-protein kinase PAK 1
5DEYB 2.1 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 59T Type1 255 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
5IMEB 2.217 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno 6BZ Type1 250 - 541 0 None None Serine/threonine-protein kinase PAK 1
9D50B 1.898 Inactive DFGinter‑None in-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1A2T Type1 253 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1
4ZJIA 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 542 0 None None Serine/threonine-protein kinase PAK 1
4ZJIB 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 540 0 None None Serine/threonine-protein kinase PAK 1
4ZJIC 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 250 - 541 0 None None Serine/threonine-protein kinase PAK 1
4ZJID 1.99 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 253 - 541 0 None None Serine/threonine-protein kinase PAK 1
4ZJJA 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 249 - 539 0 None None Serine/threonine-protein kinase PAK 1
4ZJJB 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 251 - 539 0 None None Serine/threonine-protein kinase PAK 1
4ZJJC 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 4OR Type3 251 - 542 0 None None Serine/threonine-protein kinase PAK 1
4ZJJD 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_oooo 4OR Type3 252 - 541 0 None None Serine/threonine-protein kinase PAK 1
4ZLOA 2.5 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno 4PV Type3 250 - 543 0 TPO423 None Serine/threonine-protein kinase PAK 1
5KBQB 2.58 Inactive None‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 255 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1
5KBRB 2.36 Inactive None‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno IPW Type1 255 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1
4P90B 2.49 Inactive None‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno 2K0 Type1 257 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1
3Q53A 2.09 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 250 - 541 0 TPO423 K299R,L516I Serine/threonine-protein kinase PAK 1
3Q4ZA 1.887 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 251 - 545 0 None S259I,K299R,D389N,L516I Serine/threonine-protein kinase PAK 1
4ZLOB 2.5 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 253 - 543 0 TPO423 None Serine/threonine-protein kinase PAK 1
3Q52A 1.801 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 250 - 542 0 TPO423 K299R,L516I Serine/threonine-protein kinase PAK 1
1YHWA 1.8 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 541 0 None K299R Serine/threonine-protein kinase PAK 1
8X5ZA 1.8 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 543 0 TPO423 K299R,E503D Serine/threonine-protein kinase PAK 1
1YHVA 1.8 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 541 0 None K299R,T423E Serine/threonine-protein kinase PAK 1
3FXZA 1.64 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii FLL Type1 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1
3FY0A 2.35 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1
4DAWA 2.0 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 0H2 Type1 249 - 542 0 TPO423 K299R Serine/threonine-protein kinase PAK 1
2HY81 2.0 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 1ST Type1 249 - 541 0 None K299R,T423E Serine/threonine-protein kinase PAK 1
4EQCA 2.01 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii XR1 Type1.5_Back 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1
5DFPA 2.2 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii 59U Type1.5_Front 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1

STE_PAK1 (Serine/threonine-protein kinase PAK 1)

Total number of chains: 69
Active chains: 10
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 37 53.6% AF-Q13153-K1A
DFGout BBAminus 8 11.6% 4ZJID
DFGin BLBplus 7 10.1% 4ZY5B
DFGin None 5 7.2% 5DEYB
DFGin BLAplus 4 5.8% 9N4UB
None None 3 4.3% 5KBQB
DFGin BLBminus 2 2.9% 9D4XB
DFGin ABAminus 1 1.4% 9N48B
DFGinter None 1 1.4% 9D50B
DFGout None 1 1.4% 4ZLOA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
PAK1_HUMAN AF-Q13153-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 262 - 529 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN AF-Q13153-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 262 - 529 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZY4A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZY5A 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T5 Type1 251 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZY6A 2.15 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T6 Type1 251 - 542 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4XA 1.847 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2S Type1 252 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D50A 1.898 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2T Type1 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4VA 1.84 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2P Type1 252 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4YA 1.847 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2S Type1 252 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4O0TA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2OL Type1.5_Back 251 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9N48B 1.85 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BV1 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4O0RB 2.4 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 6B16A 2.285 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii C7Y Type1 251 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 7VTOA 2.59 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 107 Type1 257 - 542 0 TPO423 None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5DEWA 1.9 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 59N Type1 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4WA 2.218 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2Q Type1 252 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4O0RA 2.4 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 7KC Type1 249 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5KBQA 2.58 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii IPV Type1 254 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5KBRA 2.36 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii IPW Type1 255 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4P90A 2.49 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 2K0 Type1 250 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9N48A 1.85 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BV1 Type1 249 - 545 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9NBXA 2.15 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BW5 Type1 249 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5DEYA 2.1 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 59T Type1.5_Back 250 - 544 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5IMEA 2.217 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii 6BZ Type1.5_Back 251 - 545 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9N4UA 1.77 Inactive DFGin‑BLAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1BV8 Type1.5_Back 249 - 545 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 1F3MC 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 1F3MD 2.3 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 249 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZY6B 2.15 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 4T6 Type1 255 - 542 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9N4UB 1.77 Inactive DFGin‑BLAplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno A1BV8 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4XB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4YB 1.847 Inactive DFGin‑BLBminus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2S Type1 256 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZY4B 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZY5B 2.35 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T5 Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 6B16B 2.285 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_nnno C7Y Type1 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5DEWB 1.9 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 59N Type1 255 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4VB 1.84 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2P Type1 252 - 543 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D4WB 2.218 Inactive DFGin‑BLBplus out-none none-out nonTYR APEdihe_aaiio APEdist_nnno A1A2Q Type1 257 - 545 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9NBXB 2.15 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1BW5 Type1 254 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4O0TB 2.6 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 255 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 3Q4ZB 1.887 Inactive DFGin‑None out-none none-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 250 - 541 0 None S259I,K299R,D389N,L516I Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 7VTOB 2.59 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 107 Type1 255 - 542 0 TPO423 None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5DEYB 2.1 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_oooo 59T Type1 255 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5IMEB 2.217 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaiio APEdist_nnno 6BZ Type1 250 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 9D50B 1.898 Inactive DFGinter‑None in-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1A2T Type1 253 - 542 0 None D389N,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJIA 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJIB 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 540 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJIC 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 250 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJID 1.99 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 253 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJJA 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 249 - 539 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJJB 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 251 - 539 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJJC 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 4OR Type3 251 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZJJD 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_oooo 4OR Type3 252 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZLOA 2.5 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno 4PV Type3 250 - 543 0 TPO423 None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5KBQB 2.58 Inactive None‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno No_ligand No_ligand 255 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5KBRB 2.36 Inactive None‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno IPW Type1 255 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4P90B 2.49 Inactive None‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno 2K0 Type1 257 - 542 0 None D389N,T423E,E503D Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 3Q53A 2.09 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ATP ATPlike 250 - 541 0 TPO423 K299R,L516I Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 3Q4ZA 1.887 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 251 - 545 0 None S259I,K299R,D389N,L516I Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4ZLOB 2.5 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 253 - 543 0 TPO423 None Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 3Q52A 1.801 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 250 - 542 0 TPO423 K299R,L516I Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 1YHWA 1.8 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 541 0 None K299R Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 8X5ZA 1.8 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 543 0 TPO423 K299R,E503D Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 1YHVA 1.8 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 249 - 541 0 None K299R,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 3FXZA 1.64 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii FLL Type1 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 3FY0A 2.35 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4DAWA 2.0 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 0H2 Type1 249 - 542 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 2HY81 2.0 None DFGin‑BLAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 1ST Type1 249 - 541 0 None K299R,T423E Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 4EQCA 2.01 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii XR1 Type1.5_Back 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens
PAK1_HUMAN 5DFPA 2.2 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii 59U Type1.5_Front 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens

STE_PAK1 (Serine/threonine-protein kinase PAK 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism