9D50

PAK1 (Serine/threonine-protein kinase PAK 1)
Group: STE
Uniprot: PAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 270 - 521
Resolu: 1.898

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in A1A2T Type1 250 - 544 0
B Inactive DFGinter None in-out none-out A1A2T Type1 253 - 542 8
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       259        269        279        289 
deeILEKLRS IVSVGDPKKK YTRFEKIGQG ASGTVYTAMD 
       299        309        319        329 
VATGQEVAIK QMNLqqqpkk eLIINEILVM RENKNPNIVN 
       339        349        359        369 
YLDSYLVGDE LWVVMEYLAG GSLTDVVTET CMDEGQIAAV 
       379        389        399        409 
CRECLQALEF LHSNQVIHRN IKSDNILLGM DGSVKLTDFG 
       419        429        439        449 
FcaqitpeqS KRSEMVGTPY WMAPEVVTRK AYGPKVDIWS 
       459        469        479        489 
LGIMAIEMIE GEPPYLNENP LRALYLIATN GTPELQNPEK 
       499        509        519        529 
LSAIFRDFLN RCLEMDVEKR GSAKELLQHQ FLKIAKPLSS 
       539 
LTPLIAAAKE ATKnnh
Lower-case residues are disordered in structure.
Mutations: D389N,T423E
Phosphorylation: None