Ligand: DW1

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 3FY0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC GSK3B GSK3B_HUMAN 3M1SA 3.134 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii DW1 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 3M1SB 3.134 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
STE PAK1 PAK1_HUMAN 3FY0A 2.35 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1

Ligand: DW1

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 3FY0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC GSK3B GSK3B_HUMAN 3M1SA 3.134 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii DW1 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
CMGC GSK3B GSK3B_HUMAN 3M1SB 3.134 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
STE PAK1 PAK1_HUMAN 3FY0A 2.35 None DFGin‑BLAminus out-none in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 249 - 541 0 TPO423 K299R Serine/threonine-protein kinase PAK 1 Homo sapiens

Ligand: DW1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism