PDB: 4ZY4 — STE PAK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4ZY4A
DFGin BLBplus 1 50.0% 4ZY4B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE PAK1 PAK1_HUMAN 4ZY4A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZY4B 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1

PDB: 4ZY4 — STE PAK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4ZY4A
DFGin BLBplus 1 50.0% 4ZY4B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE PAK1 PAK1_HUMAN 4ZY4A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZY4B 2.6 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaiio APEdist_oooo 4T3 Type1 249 - 541 0 None D389N Serine/threonine-protein kinase PAK 1 Homo sapiens

PDB: 4ZY4 — STE PAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism