TYR_ABL1 (Tyrosine-protein kinase ABL1)

Total number of chains: 96
Active chains: 11
Uniprot: ABL1_HUMAN
Kinase Domain Residues: 242 - 495
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 29 30.2% 3QRJB
DFGinter None 26 27.1% 2G2HA
DFGin BLAminus 16 16.7% AF-P00519-K1A
DFGout None 15 15.6% 2HZIA
DFGin BLBplus 6 6.2% 2G1TA
DFGinter BABtrans 3 3.1% 7W7XA
None None 1 1.0% 4WA9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
2HZ4C 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4ST Allosteric 234 - 500 0 None None Tyrosine-protein kinase ABL1
7N9GB 2.2 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai STI, 1N1 Allosteric, Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1
AF-P00519-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 234 - 503 0 None None Tyrosine-protein kinase ABL1
AF-P00519-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 234 - 503 0 None None Tyrosine-protein kinase ABL1
4TWPA 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 233 - 503 0 None T315I Tyrosine-protein kinase ABL1
4TWPB 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 233 - 503 0 None T315I Tyrosine-protein kinase ABL1
2V7AA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 627 Type1 233 - 503 0 PTR393 T315I Tyrosine-protein kinase ABL1
2V7AB 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 627 Type1 234 - 503 0 PTR393 T315I Tyrosine-protein kinase ABL1
2HZ4B 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4ST Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1
2F4JA 1.91 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 227 - 513 0 None H396P Tyrosine-protein kinase ABL1
2GQGB 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1.5_Back 229 - 499 0 PTR393 None Tyrosine-protein kinase ABL1
2G2IA 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 229 - 502 0 None H396P Tyrosine-protein kinase ABL1
2G2IB 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 232 - 500 0 None H396P Tyrosine-protein kinase ABL1
2HZ4A 2.8 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai 4ST Allosteric 234 - 500 0 None None Tyrosine-protein kinase ABL1
6XR6A 999.0 Inactive DFGin‑BLAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None None Tyrosine-protein kinase ABL1
2GQGA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1N1 Type1 229 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
8SSNB 2.86 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1 64 - 506 0 None None Tyrosine-protein kinase ABL1
8SSNA 2.86 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1.5_Back 64 - 507 0 None None Tyrosine-protein kinase ABL1
2G1TA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 502 0 None None Tyrosine-protein kinase ABL1
2G1TB 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 230 - 502 0 None None Tyrosine-protein kinase ABL1
2G1TC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 507 0 None None Tyrosine-protein kinase ABL1
2G1TD 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 229 - 502 0 None None Tyrosine-protein kinase ABL1
7W7XA 2.0 Inactive DFGinter‑BABtrans in-out out-in TYR APEdihe_iiiai APEdist_aaai 8DW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
7W7XB 2.0 Inactive DFGinter‑BABtrans in-out out-in TYR APEdihe_iiiai APEdist_aaai 8DW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
4XEYB 2.891 Inactive DFGinter‑BABtrans in-out out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 122 - 504 0 None None Tyrosine-protein kinase ABL1
7N9GA 2.2 Inactive DFGinter‑None in-out out-none TYR APEdihe_nniai APEdist_aaai STI, 1N1 Allosteric, Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1
7N9GC 2.2 Inactive DFGinter‑None in-none out-none TYR APEdihe_nniai APEdist_aaai STI, 1N1 Allosteric, Type1 234 - 499 0 None None Tyrosine-protein kinase ABL1
2G2FA 2.7 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 232 - 506 0 None H396P Tyrosine-protein kinase ABL1
6BL8A 2.5 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1
6BL8B 2.5 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 504 0 None None Tyrosine-protein kinase ABL1
8I7SA 1.946 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
8I7SB 1.946 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
8I7ZB 2.255 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
7W7YA 2.2 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 8IW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
7W7YB 2.2 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 8IW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
8H7FA 2.45 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QEW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
8H7FB 2.45 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QEW Type1 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
8H7HA 2.278 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QH9 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
8H7HB 2.278 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QH9 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
4ZOGA 2.3 Inactive DFGinter‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 233 - 501 0 None None Tyrosine-protein kinase ABL1
7CC2A 2.723 Inactive DFGinter‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai FVC Type1 233 - 501 0 None None Tyrosine-protein kinase ABL1
7CC2B 2.723 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai FVC Type1 232 - 501 0 None None Tyrosine-protein kinase ABL1
7DT2A 2.3 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai HJ9 Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1
7DT2B 2.3 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai HJ9 Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1
2G2HA 2.0 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1 233 - 504 0 None H396P Tyrosine-protein kinase ABL1
4XEYA 2.891 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 231 - 503 0 None None Tyrosine-protein kinase ABL1
8I7ZA 2.255 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai 6CI, BAL Type1, Type1 232 - 499 0 PTR393 None Tyrosine-protein kinase ABL1
4YC8A 2.9 Inactive DFGinter‑None out-none out-in TYR APEdihe_iiiai APEdist_aaai 4B7 Type1.5_Front 233 - 501 0 None None Tyrosine-protein kinase ABL1
4YC8B 2.9 Inactive DFGinter‑None out-none out-in TYR APEdihe_iiiai APEdist_aaai 4B7 Type1.5_Front 233 - 502 0 None None Tyrosine-protein kinase ABL1
9KS5A 2.2 Inactive DFGinter‑None in-na out-in TYR APEdihe_iiiai APEdist_aaai A1EG1 Type1.5_Front 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
9KS5B 2.2 Inactive DFGinter‑None in-na out-in TYR APEdihe_iiiai APEdist_aaai A1EG1 Type1.5_Front 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
6XRGA 999.0 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None G250E,M290L,T389Y Tyrosine-protein kinase ABL1
3QRJA 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 234 - 496 0 None T315I Tyrosine-protein kinase ABL1
3QRJB 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 233 - 497 0 None T315I Tyrosine-protein kinase ABL1
2HZ0A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GIN Type2 233 - 497 0 None None Tyrosine-protein kinase ABL1
2HZ0B 2.1 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan GIN Type2 228 - 497 0 None None Tyrosine-protein kinase ABL1
2HYYA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 235 - 498 0 None None Tyrosine-protein kinase ABL1
2HYYB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
2HYYC 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
2HYYD 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
3CS9A 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
3CS9B 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
3CS9C 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 232 - 497 0 None None Tyrosine-protein kinase ABL1
3CS9D 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
3QRIA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1
3QRIB 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 232 - 498 0 None None Tyrosine-protein kinase ABL1
2HIWA 2.2 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1
2HIWB 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1
2E2BA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1
2E2BB 2.2 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 497 0 None None Tyrosine-protein kinase ABL1
5HU9A 1.529 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 66K, 66K Type2, Allosteric 229 - 499 0 None None Tyrosine-protein kinase ABL1
3PYYA 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, 3YY Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
3PYYB 1.85 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao STI, 3YY Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
6NPEA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWD Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
6NPEB 2.15 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai STI, KWD Type2, Allosteric 233 - 511 0 None None Tyrosine-protein kinase ABL1
6NPUA 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
6NPUB 2.33 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
6NPVA 1.86 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
6NPVB 1.86 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
3QRKA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 9DP Type3 229 - 496 0 None None Tyrosine-protein kinase ABL1
2G2FB 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 234 - 502 0 None H396P Tyrosine-protein kinase ABL1
6XR7A 999.0 Inactive DFGout‑None in-in out-out TYR APEdihe_ooiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None None Tyrosine-protein kinase ABL1
8I7TB 2.8 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6I5 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
2HZIA 1.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai JIN Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1
4ZOGB 2.3 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 234 - 503 0 None None Tyrosine-protein kinase ABL1
4WA9B 2.2 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 246 - 508 0 None None Tyrosine-protein kinase ABL1
3UE4A 2.424 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai DB8 Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1
3UE4B 2.424 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai DB8 Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1
8I7TA 2.8 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6I5 Type1.5_Back 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
2HZIB 1.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai JIN Type1.5_Back 233 - 500 0 None None Tyrosine-protein kinase ABL1
2G2HB 2.0 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 233 - 504 0 None H396P Tyrosine-protein kinase ABL1
2FO0A 2.27 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 46 - 511 0 SEP50 D363N Tyrosine-protein kinase ABL1
1OPLA 3.42 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 62 - 512 0 None K12R,D363N Tyrosine-protein kinase ABL1
1OPLB 3.42 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 121 - 499 0 None K12R,D363N Tyrosine-protein kinase ABL1
5MO4A 2.17 Inactive DFGout‑None in-in none-out TYR APEdihe_nnoai APEdist_aaao NIL, AY7 Type2, Allosteric 64 - 512 0 None None Tyrosine-protein kinase ABL1
4WA9A 2.2 Inactive None‑None none-none out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 246 - 504 0 None None Tyrosine-protein kinase ABL1

TYR_ABL1 (Tyrosine-protein kinase ABL1)

Total number of chains: 136
Active chains: 16
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 55 40.4% 3KFAA
DFGinter None 31 22.8% 2G2HA
DFGin BLAminus 21 15.4% AF-P00519-K1A
DFGout None 18 13.2% 2HZIA
DFGin BLBplus 6 4.4% 2G1TA
DFGinter BABtrans 3 2.2% 7W7XA
None None 2 1.5% 3DK7B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
ABL1_HUMAN 2HZ4C 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4ST Allosteric 234 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7N9GB 2.2 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai STI, 1N1 Allosteric, Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN AF-P00519-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 234 - 503 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN AF-P00519-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 234 - 503 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4TWPA 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 233 - 503 0 None T315I Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4TWPB 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 233 - 503 0 None T315I Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2V7AA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 627 Type1 233 - 503 0 PTR393 T315I Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2V7AB 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 627 Type1 234 - 503 0 PTR393 T315I Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HZ4B 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 4ST Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2F4JA 1.91 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 227 - 513 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2GQGB 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1.5_Back 229 - 499 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G2IA 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 229 - 502 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G2IB 3.12 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ADP ATPlike 232 - 500 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HZ4A 2.8 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai 4ST Allosteric 234 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6XR6A 999.0 Inactive DFGin‑BLAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2GQGA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1N1 Type1 229 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8SSNB 2.86 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1 64 - 506 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8SSNA 2.86 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan AY7, SKI Allosteric, Type1.5_Back 64 - 507 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G1TA 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G1TB 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 230 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G1TC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 232 - 507 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G1TD 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 229 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7W7XA 2.0 Inactive DFGinter‑BABtrans in-out out-in TYR APEdihe_iiiai APEdist_aaai 8DW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7W7XB 2.0 Inactive DFGinter‑BABtrans in-out out-in TYR APEdihe_iiiai APEdist_aaai 8DW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4XEYB 2.891 Inactive DFGinter‑BABtrans in-out out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 122 - 504 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7N9GA 2.2 Inactive DFGinter‑None in-out out-none TYR APEdihe_nniai APEdist_aaai STI, 1N1 Allosteric, Type1 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7N9GC 2.2 Inactive DFGinter‑None in-none out-none TYR APEdihe_nniai APEdist_aaai STI, 1N1 Allosteric, Type1 234 - 499 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G2FA 2.7 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 232 - 506 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6BL8A 2.5 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6BL8B 2.5 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai PVB Type1 233 - 504 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8I7SA 1.946 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8I7SB 1.946 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8I7ZB 2.255 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6CI Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7W7YA 2.2 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 8IW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7W7YB 2.2 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 8IW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8H7FA 2.45 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QEW Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8H7FB 2.45 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QEW Type1 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8H7HA 2.278 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QH9 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8H7HB 2.278 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai QH9 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4ZOGA 2.3 Inactive DFGinter‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 233 - 501 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7CC2A 2.723 Inactive DFGinter‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai FVC Type1 233 - 501 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7CC2B 2.723 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai FVC Type1 232 - 501 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7DT2A 2.3 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai HJ9 Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 7DT2B 2.3 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai HJ9 Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G2HA 2.0 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1 233 - 504 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4XEYA 2.891 Inactive DFGinter‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1 231 - 503 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8I7ZA 2.255 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai 6CI, BAL Type1, Type1 232 - 499 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4YC8A 2.9 Inactive DFGinter‑None out-none out-in TYR APEdihe_iiiai APEdist_aaai 4B7 Type1.5_Front 233 - 501 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4YC8B 2.9 Inactive DFGinter‑None out-none out-in TYR APEdihe_iiiai APEdist_aaai 4B7 Type1.5_Front 233 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 9KS5A 2.2 Inactive DFGinter‑None in-na out-in TYR APEdihe_iiiai APEdist_aaai A1EG1 Type1.5_Front 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 9KS5B 2.2 Inactive DFGinter‑None in-na out-in TYR APEdihe_iiiai APEdist_aaai A1EG1 Type1.5_Front 233 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6XRGA 999.0 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None G250E,M290L,T389Y Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3QRJA 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 234 - 496 0 None T315I Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3QRJB 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 233 - 497 0 None T315I Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HZ0A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GIN Type2 233 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HZ0B 2.1 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan GIN Type2 228 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HYYA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 235 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HYYB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HYYC 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HYYD 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3CS9A 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3CS9B 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3CS9C 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 232 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3CS9D 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3QRIA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3QRIB 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 232 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HIWA 2.2 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HIWB 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2E2BA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2E2BB 2.2 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 5HU9A 1.529 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 66K, 66K Type2, Allosteric 229 - 499 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3PYYA 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, 3YY Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3PYYB 1.85 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao STI, 3YY Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6NPEA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWD Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6NPEB 2.15 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai STI, KWD Type2, Allosteric 233 - 511 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6NPUA 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6NPUB 2.33 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6NPVA 1.86 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6NPVB 1.86 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3QRKA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 9DP Type3 229 - 496 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G2FB 2.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai AGS ATPlike 234 - 502 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 6XR7A 999.0 Inactive DFGout‑None in-in out-out TYR APEdihe_ooiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8I7TB 2.8 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6I5 Type1 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HZIA 1.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai JIN Type1 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4ZOGB 2.3 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai VX6 Type1 234 - 503 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4WA9B 2.2 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 246 - 508 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3UE4A 2.424 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai DB8 Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 3UE4B 2.424 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai DB8 Type1 233 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 8I7TA 2.8 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6I5 Type1.5_Back 232 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2HZIB 1.7 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai JIN Type1.5_Back 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2G2HB 2.0 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 233 - 504 0 None H396P Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 2FO0A 2.27 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 46 - 511 0 SEP50 D363N Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 1OPLA 3.42 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 62 - 512 0 None K12R,D363N Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 1OPLB 3.42 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 121 - 499 0 None K12R,D363N Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 5MO4A 2.17 Inactive DFGout‑None in-in none-out TYR APEdihe_nnoai APEdist_aaao NIL, AY7 Type2, Allosteric 64 - 512 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_HUMAN 4WA9A 2.2 Inactive None‑None none-none out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 246 - 504 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
ABL1_MOUSE 2Z60A 1.95 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai P3Y Type1 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 2QOHA 1.95 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai P3Y Type1 229 - 501 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 2QOHB 1.95 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai P3Y Type1 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KF4A 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai B90 Type1.5_Back 229 - 514 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KF4B 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai B90 Type1.5_Back 229 - 501 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK7A 2.01 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 502 0 PTR393 T315I,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK6A 2.02 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 502 0 PTR393 Y253F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK6B 2.02 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 234 - 505 0 PTR393 Y253F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK3A 2.02 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 502 0 None Y393F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK3B 2.02 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 505 0 None Y393F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3K5VA 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3K5VB 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD4A 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD4B 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD6A 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYH, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3OY3A 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3OY3B 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3IK3A 1.9 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3IK3B 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3OXZA 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao 0LI Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KFAA 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KFAB 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1FPUA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1FPUB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1IEPA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1IEPB 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1OPJA 1.75 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1OPJB 1.75 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 512 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 2HZNA 2.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai KIN Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD6B 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MS9A 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 230 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MS9B 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSA 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSB 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSC 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSD 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1M52A 2.6 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P17 Type1.5_Back 232 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1M52B 2.6 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P17 Type1.5_Back 232 - 503 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1OPKA 1.8 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 64 - 512 0 None D363N Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK7B 2.01 Inactive None‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 505 0 PTR393 T315I,L445P Tyrosine-protein kinase ABL1 Mus musculus

TYR_ABL1 (Tyrosine-protein kinase ABL1)

Total number of chains: 40
Active chains: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 26 65.0% 3KFAA
DFGin BLAminus 5 12.5% 3KF4B
DFGinter None 5 12.5% 3DK7A
DFGout None 3 7.5% 1OPKA
None None 1 2.5% 3DK7B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
ABL1_MOUSE 2Z60A 1.95 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai P3Y Type1 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 2QOHA 1.95 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai P3Y Type1 229 - 501 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 2QOHB 1.95 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai P3Y Type1 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KF4A 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai B90 Type1.5_Back 229 - 514 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KF4B 1.9 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai B90 Type1.5_Back 229 - 501 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK7A 2.01 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 502 0 PTR393 T315I,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK6A 2.02 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 502 0 PTR393 Y253F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK6B 2.02 Inactive DFGinter‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 234 - 505 0 PTR393 Y253F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK3A 2.02 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 502 0 None Y393F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK3B 2.02 Inactive DFGinter‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 505 0 None Y393F,L445P Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3K5VA 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3K5VB 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD4A 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD4B 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD6A 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYH, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3OY3A 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3OY3B 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3IK3A 1.9 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3IK3B 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3OXZA 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao 0LI Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KFAA 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3KFAB 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1FPUA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1FPUB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1IEPA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1IEPB 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1OPJA 1.75 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1OPJB 1.75 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 512 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 2HZNA 2.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai KIN Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 6HD6B 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MS9A 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 230 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MS9B 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSA 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSB 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSC 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3MSSD 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1M52A 2.6 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P17 Type1.5_Back 232 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1M52B 2.6 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P17 Type1.5_Back 232 - 503 0 None None Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 1OPKA 1.8 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai P16 Type1.5_Back 64 - 512 0 None D363N Tyrosine-protein kinase ABL1 Mus musculus
ABL1_MOUSE 3DK7B 2.01 Inactive None‑None in-none out-in TYR APEdihe_iiiai APEdist_aaai SX7 Type1 233 - 505 0 PTR393 T315I,L445P Tyrosine-protein kinase ABL1 Mus musculus