2FST

MAPK14 (Mitogen-activated protein kinase 14)
Group: CMGC
Uniprot: MK14_HUMAN
Organism: Homo sapiens
Domain boundary: 24 - 308
Resolu: 1.45

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
X Inactive None None in-in none-out No_ligand No_ligand 5 - 352 15
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain X
         3         13         23         33 
mahhhhhhsq eRPTFYRQEL NKTIWEVPER YQNLSPVGsg 
        43         53         63         73 
ayGSVCAAFD TKTGLRVAVK KLSRPFQSII HAKRTYRELR 
        83         93        103        113 
LLKHMKHENV IGLLDVFTPA RSLEEFNDVY LVTHLMGADL 
       123        133        143        153 
NnivkcQKLT DDHVQFLIYQ ILRGLKYIHS ADIIHRDLKP 
       163        173        183        193 
SNLAVNEDCE LKILDfglar htademtgyv ATRWYRAPEI 
       203        213        223        233 
MLNWMHYNQT VDIWSVGCIM AELLTGRTLF PGTDHIDQLK 
       243        253        263        273 
LILRLVGTPG AELLKKISSE SARNYIQSLT QMPKMNFANV 
       283        293        303        313 
FIGANPLAVD LLEKMLVLDS DKRITAAQAL AHAYFAQYHD 
       323        333        343        353 
PDDEPVADPY DQSLESRDLL IDEWKSLTYD EVISFVPPPl 

dqeemes
Lower-case residues are disordered in structure.
Mutations: D176A,F327L
Phosphorylation: None