4TYH

MAPKAPK2 (MAP kinase-activated protein kinase 2)
MAPK14 (Mitogen-activated protein kinase 14)
Group: CMGC CAMK
Uniprot: MK14_MOUSE MAPK2_HUMAN
Organism: Homo sapiens Mus musculus
Domain boundary: 63 - 325 24 - 308
Resolution: 3.0

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 Homo sapiens Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 51 - 400 0
B CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 Mus musculus None DFGin BLAminus out-out none-out 39G Type1.5_Back 6 - 353 8
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        15         25         35         45 
PTFYRQELNK TIWEVPERYQ NLSPVGSGAY GSVCAAFDTK 
        55         65         75         85 
TGHRVAVKKL SRPFQSIIHA KRTYRELRLL KHMKHENVIG 
        95        105        115        125 
LLDVFTPARS LEEFNDVYLV THLMGADLNN IVKCQKLTDD 
       135        145        155        165 
HVQFLIYQIL RGLKYIHSAD IIHRDLKPSN LAVNEDCELK 
       175        185        195        205 
ILDFGLArht ddemtGYVAT RWYRAPEIMl nwmhYNQTVD 
       215        225        235        245 
IWSVGCIMAE LLTGRTLFPG TDHIDQLKLI LRLVGTPGAE 
       255        265        275        285 
LLKKISSESA RNYIQSLAQM PKMNFANVFI GANPLAVDLL 
       295        305        315        325 
EKMLVLDSDK RITAAQALAH AYFAQYHDPD DEPVADPYDQ 
       335        345 
SFESRDLLID EWKSLTYDEV ISFVPPPL
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None