3HEC

MAPK14 (Mitogen-activated protein kinase 14)
Group: CMGC
Uniprot: MK14_HUMAN
Organism: Homo sapiens
Domain boundary: 24 - 308
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None in-in none-out STI Type2 5 - 352 14
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        14         24         34         44 
RPTFYRQELN KTIWEVPERY QNLSPVGsga ygSVCAAFDT 
        54         64         74         84 
KTGLRVAVKK LSRPFQSIIH AKRTYRELRL LKHMKHENVI 
        94        104        114        124 
GLLDVFTPAR SLEEFNDVYL VTHLMGADLN NIVKCQKLTD 
       134        144        154        164 
DHVQFLIYQI LRGLKYIHSA DIIHRDLKPS NLAVNEDCEL 
       174        184        194        204 
KILDFglarh tddemtgyvA TRWYRAPEIM LNWMHYNQTV 
       214        224        234        244 
DIWSVGCIMA ELLTGRTLFP GTDHIDQLKL ILRLVGTPGA 
       254        264        274        284 
ELLKKISSES ARNYIQSLTQ MPKMNFANVF IGANPLAVDL 
       294        304        314        324 
LEKMLVLDSD KRITAAQALA HAYFAQYHDP DDEPVADPYD 
       334        344 
QSFESRDLLI DEWKSLTYDE VISFVPPP
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None