AGC_ROCK1 (Rho-associated protein kinase 1)

Total number of chains: 78
Active chains: 22
Uniprot: ROCK1_HUMAN
Kinase Domain Residues: 76 - 338
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 48 61.5% AF-Q13464-K1A
DFGin ABAminus 22 28.2% 5WNFA
DFGout None 3 3.8% 7S25B
DFGinter None 2 2.6% 3TWJB
DFGin BLBminus 1 1.3% 7S26C
DFGin None 1 1.3% 3TWJC
None None 1 1.3% 7S25D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
2V55A 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1
2V55C 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1
AF-Q13464-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 68 - 346 0 None None Rho-associated protein kinase 1
AF-Q13464-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 68 - 346 0 None None Rho-associated protein kinase 1
4W7PA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 405 0 None None Rho-associated protein kinase 1
4W7PB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 401 0 None None Rho-associated protein kinase 1
4W7PC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 401 0 None None Rho-associated protein kinase 1
4W7PD 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 403 0 None None Rho-associated protein kinase 1
2ESMA 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 6 - 405 0 None None Rho-associated protein kinase 1
2ETKA 2.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HFS Type1 6 - 405 0 None None Rho-associated protein kinase 1
2ETRA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y27 Type1 6 - 405 0 None None Rho-associated protein kinase 1
3D9VA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H52 Type1 6 - 405 0 None None Rho-associated protein kinase 1
4YVCA 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4KH Type1 6 - 405 0 None None Rho-associated protein kinase 1
4YVEA 3.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4KK Type1 6 - 405 0 None None Rho-associated protein kinase 1
5BMLA 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4TW Type1 6 - 405 0 None None Rho-associated protein kinase 1
5KKSA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6U1 Type1 6 - 405 0 None None Rho-associated protein kinase 1
5KKTA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6U2 Type1 6 - 405 0 None None Rho-associated protein kinase 1
5UZJA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8UV Type1 6 - 405 0 None None Rho-associated protein kinase 1
5HVUA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65R Type1.5_Front 6 - 405 0 None None Rho-associated protein kinase 1
5WNEA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4J Type1.5_Front 14 - 400 0 None None Rho-associated protein kinase 1
5WNEC 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4J Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1
5WNED 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4J Type1.5_Front 7 - 402 0 None None Rho-associated protein kinase 1
3NDMA 3.3 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 402 0 None None Rho-associated protein kinase 1
3NCZA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1
3NCZB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1
3NCZC 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 404 0 None None Rho-associated protein kinase 1
3NCZD 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1
3NDMB 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1
3NDMC 3.3 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 3ND Type1 6 - 402 0 None None Rho-associated protein kinase 1
3NDMD 3.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1
5WNFA 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 7 - 401 0 None None Rho-associated protein kinase 1
5WNFB 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1
5WNFC 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1
5WNFD 2.45 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4V Type1 7 - 402 0 None None Rho-associated protein kinase 1
5WNGA 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 7 - 401 0 None None Rho-associated protein kinase 1
5WNGB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1
5WNGC 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1
5WNGD 2.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4Y Type1 7 - 402 0 None None Rho-associated protein kinase 1
5WNHA 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 401 0 None None Rho-associated protein kinase 1
5WNHB 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1
5WNHC 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1
5WNHD 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1
6E9WA 2.96 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 9 - 404 0 None None Rho-associated protein kinase 1
6E9WB 2.96 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo J0P Type1 7 - 401 0 None None Rho-associated protein kinase 1
7S26D 2.744 Inactive DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 6 - 399 0 None None Rho-associated protein kinase 1
8ZH5A 3.7 Inactive DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 6 - 402 0 None None Rho-associated protein kinase 1
7S26A 2.744 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 86K Type1 6 - 401 0 None None Rho-associated protein kinase 1
3TV7A 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iiio 07Q Type1 9 - 402 0 None None Rho-associated protein kinase 1
3TV7B 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oioo 07Q Type1 6 - 402 0 None None Rho-associated protein kinase 1
3TV7C 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iiio 07Q Type1 9 - 402 0 None None Rho-associated protein kinase 1
3TV7D 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_oioo 07Q Type1 6 - 402 0 None None Rho-associated protein kinase 1
3V8SA 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 0HD Type1 8 - 402 0 None None Rho-associated protein kinase 1
3V8SB 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio 0HD Type1 6 - 402 0 None None Rho-associated protein kinase 1
3V8SC 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 0HD Type1 8 - 402 0 None None Rho-associated protein kinase 1
3V8SD 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo 0HD Type1 6 - 402 0 None None Rho-associated protein kinase 1
7JOUA 3.318 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii VFS Type1 9 - 402 0 None None Rho-associated protein kinase 1
2ESMB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo M77 Type1 6 - 402 0 None None Rho-associated protein kinase 1
2ETKB 2.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo HFS Type1 6 - 402 0 None None Rho-associated protein kinase 1
2ETRB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo Y27 Type1 6 - 402 0 None None Rho-associated protein kinase 1
3D9VB 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo H52 Type1 6 - 402 0 None None Rho-associated protein kinase 1
4YVCB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 4KH Type1 6 - 402 0 None None Rho-associated protein kinase 1
4YVEB 3.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iiio 4KK Type1 6 - 402 0 None None Rho-associated protein kinase 1
5BMLB 2.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 4TW Type1 6 - 402 0 None None Rho-associated protein kinase 1
5UZJB 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 8UV Type1 6 - 402 0 None None Rho-associated protein kinase 1
3TWJA 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 07R Type1.5_Back 7 - 402 0 None None Rho-associated protein kinase 1
5HVUB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 65R Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1
5KKSB 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo 6U1 Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1
5KKTB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 6U2 Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1
7S26C 2.744 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 86K Type1 8 - 402 0 None None Rho-associated protein kinase 1
3TWJC 2.9 Inactive DFGin‑None in-out out-out nonTYR APEdihe_aaoii APEdist_oiio 07R Type1 7 - 402 0 None None Rho-associated protein kinase 1
3TWJB 2.9 Inactive DFGinter‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 8 - 402 0 None None Rho-associated protein kinase 1
3TWJD 2.9 Inactive DFGinter‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 8 - 402 0 None None Rho-associated protein kinase 1
7S25A 2.337 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 86G Type1 7 - 401 0 None None Rho-associated protein kinase 1
7S25B 2.337 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_iioo 86G Type1 8 - 402 0 None None Rho-associated protein kinase 1
7S25C 2.337 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 86G Type1 13 - 402 0 None None Rho-associated protein kinase 1
7S25D 2.337 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 401 0 None None Rho-associated protein kinase 1
7S26B 2.744 None DFGin‑BLAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 86K Type1 6 - 402 0 None None Rho-associated protein kinase 1
5WNEB 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B4J Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1

AGC_ROCK1 (Rho-associated protein kinase 1)

Total number of chains: 78
Active chains: 22
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 48 61.5% AF-Q13464-K1A
DFGin ABAminus 22 28.2% 5WNFA
DFGout None 3 3.8% 7S25B
DFGinter None 2 2.6% 3TWJB
DFGin BLBminus 1 1.3% 7S26C
DFGin None 1 1.3% 3TWJC
None None 1 1.3% 7S25D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
ROCK1_HUMAN 2V55A 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 2V55C 3.705 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN AF-Q13464-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 68 - 346 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN AF-Q13464-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 68 - 346 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4W7PA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4W7PB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4W7PC 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4W7PD 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3J7 Type1 6 - 403 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 2ESMA 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii M77 Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 2ETKA 2.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HFS Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 2ETRA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Y27 Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3D9VA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii H52 Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4YVCA 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4KH Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4YVEA 3.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4KK Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5BMLA 2.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 4TW Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5KKSA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6U1 Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5KKTA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6U2 Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5UZJA 3.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 8UV Type1 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5HVUA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65R Type1.5_Front 6 - 405 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNEA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4J Type1.5_Front 14 - 400 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNEC 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4J Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNED 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4J Type1.5_Front 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NDMA 3.3 Inactive DFGin‑ABAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NCZA 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NCZB 3.0 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NCZC 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NCZD 3.0 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NC Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NDMB 3.3 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NDMC 3.3 Inactive DFGin‑ABAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 3ND Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3NDMD 3.3 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3ND Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNFA 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNFB 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNFC 2.45 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4V Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNFD 2.45 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4V Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNGA 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNGB 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNGC 2.9 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4Y Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNGD 2.9 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4Y Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNHA 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNHB 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanio APEdist_nnnn B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNHC 3.1 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNHD 3.1 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B5G Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 6E9WA 2.96 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J0P Type1 9 - 404 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 6E9WB 2.96 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo J0P Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S26D 2.744 Inactive DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 6 - 399 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 8ZH5A 3.7 Inactive DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S26A 2.744 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 86K Type1 6 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TV7A 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iiio 07Q Type1 9 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TV7B 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_oioo 07Q Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TV7C 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iiio 07Q Type1 9 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TV7D 2.75 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_oioo 07Q Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3V8SA 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 0HD Type1 8 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3V8SB 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiio 0HD Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3V8SC 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 0HD Type1 8 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3V8SD 2.286 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioo 0HD Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7JOUA 3.318 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii VFS Type1 9 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 2ESMB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo M77 Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 2ETKB 2.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo HFS Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 2ETRB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo Y27 Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3D9VB 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo H52 Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4YVCB 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 4KH Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 4YVEB 3.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iiio 4KK Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5BMLB 2.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 4TW Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5UZJB 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iioo 8UV Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TWJA 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 07R Type1.5_Back 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5HVUB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 65R Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5KKSB 3.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_iioo 6U1 Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5KKTB 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iioo 6U2 Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S26C 2.744 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 86K Type1 8 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TWJC 2.9 Inactive DFGin‑None in-out out-out nonTYR APEdihe_aaoii APEdist_oiio 07R Type1 7 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TWJB 2.9 Inactive DFGinter‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 8 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 3TWJD 2.9 Inactive DFGinter‑None in-in out-out nonTYR APEdihe_aaioi APEdist_iioi No_ligand No_ligand 8 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S25A 2.337 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 86G Type1 7 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S25B 2.337 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaiii APEdist_iioo 86G Type1 8 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S25C 2.337 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 86G Type1 13 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S25D 2.337 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 9 - 401 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 7S26B 2.744 None DFGin‑BLAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn 86K Type1 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens
ROCK1_HUMAN 5WNEB 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn B4J Type1.5_Front 6 - 402 0 None None Rho-associated protein kinase 1 Homo sapiens

AGC_ROCK1 (Rho-associated protein kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism