4W7P

ROCK1 (Rho-associated protein kinase 1)
Group: AGC
Uniprot: ROCK1_HUMAN
Organism: Homo sapiens
Domain boundary: 76 - 338
Resolu: 2.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 3J7 Type1 6 - 405 0
B Active DFGin BLAminus in-in in-in 3J7 Type1 6 - 401 0
C Active DFGin BLAminus in-in in-in 3J7 Type1 6 - 401 0
D Active DFGin BLAminus in-in in-in 3J7 Type1 6 - 403 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
         9         19         29         39 
gastgdSFET RFEKMDNLLR DPKSEVNSDC LLDGLDALVY 
        49         59         69         79 
DLDFPALRKN KNIDNFLSRY KDTINKIRDL RMKAEDYEVV 
        89         99        109        119 
KVIGRGAFGE VQLVRHKSTR KVYAMKLLSK FEMIKRSdsa 
       129        139        149        159 
FFWEERDIMA FANSPWVVQL FYAFQDDRYL YMVMEYMPGG 
       169        179        189        199 
DLVNLMSNYD VPEKWARFYT AEVVLALDAI HSMGFIHRDV 
       209        219        229        239 
KPDNMLLDKS GHLKLADFGT CMKMNKEGMV RCDTAVGTPD 
       249        259        269        279 
YISPEVLKSq ggDGYYGREC DWWSVGVFLY EMLVGDTPFY 
       289        299        309        319 
ADSLVGTYSK IMNHKNSLTF PDDNDISKEA KNLICAFLTD 
       329        339        349        359 
REVRLGRNGV EEIKRHLFFK NDQWAWETLR DTVAPVVPDL 
       369        379        389        399 
SSDIDTSNFD DLEedkgeEE TFPIPKAFVG NQLPFVGFTY 
       409 
YSNRrylssa n
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None