5HVU

ROCK1 (Rho-associated protein kinase 1)
Group: AGC
Uniprot: ROCK1_HUMAN
Organism: Homo sapiens
Domain boundary: 76 - 338
Resolu: 2.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 65R Type1.5_Front 6 - 405 0
B None DFGin BLAminus in-in in-none 65R Type1.5_Front 6 - 402 4
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        10         20         30         40 
gslhMSFETR FEKMDNLLRD PKSEVNSDCL LDGLDALVYD 
        50         60         70         80 
LDFPALRKNK NIDNFLSRYK DTINKIRDLR MKAEDYEVVK 
        90        100        110        120 
VIGRGAFGEV QLVRHKSTRK VYAMKLLSKF EMIKRSDSAF 
       130        140        150        160 
FWEERDIMAF ANSPWVVQLF YAFQDDRYLY MVMEYMPGGD 
       170        180        190        200 
LVNLMSNYDV PEKWARFYTA EVVLALDAIH SMGFIHRDVK 
       210        220        230        240 
PDNMLLDKSG HLKLADFGTC MKMNKEGMVR CDtavgTPDY 
       250        260        270        280 
ISPEVLKSQG GDGYYGRECD WWSVGVFLYE MLVGDTPFYA 
       290        300        310        320 
DSLVGTYSKI MNHKNSLTFP DDNDISKEAK NLICAFLTDR 
       330        340        350        360 
EVRLGRNGVE EIKRHLFFKN DQWAWETLRD TVAPVVPDLS 
       370        380        390        400 
SDIDTSNFDD LEEDKGEEET FPIPKAFVGN QLPFVGFTYY 
       410 
SNrrylssan pndnr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None