3V8S

ROCK1 (Rho-associated protein kinase 1)
Group: AGC
Uniprot: ROCK1_HUMAN
Organism: Homo sapiens
Domain boundary: 76 - 338
Resolu: 2.286

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 0HD Type1 8 - 402 0
B Inactive DFGin BLAminus in-in in-out 0HD Type1 6 - 402 0
C Active DFGin BLAminus in-in in-in 0HD Type1 8 - 402 0
D Inactive DFGin BLAminus in-in in-out 0HD Type1 6 - 402 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        15         25         35         45 
SFETRFEKMD NLLRDPKSEV NSDCLLDGLD ALVYDLDFPA 
        55         65         75         85 
LRKNKNIDNF LSRYKDTINK IRDLRMKAED YEVVKVIGRG 
        95        105        115        125 
AFGEVQLVRH KSTRKVYAMK LLSKFEMIKR SDSAFFWEER 
       135        145        155        165 
DIMAFANSPW VVQLFYAFQD DRYLYMVMEY MPGGDLVNLM 
       175        185        195        205 
SNYDVPEKWA RFYTAEVVLA LDAIHSMGFI HRDVKPDNML 
       215        225        235        245 
LDKSGHLKLA DFGTCMKMNK EGMVRCDTAV GTPDYISPEV 
       255        265        275        285 
LKSQGGDGYY GRECDWWSVG VFLYEMLVGD TPFYADSLVG 
       295        305        315        325 
TYSKIMNHKN SLTFPDDNDI SKEAKNLICA FLTDREVRLG 
       335        345        355        365 
RNGVEEIKRH LFFKNDQWAW ETLRDTVAPV VPDLSSDIDT 
       375        385        395        405 
SNFDDLEEDK GEEETFPIPK AFVGNQLPFV GFTYYSNrry 
       415 
lssanpndnr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None