Ligand

Protein kinases in complex with HFS

Total number of genes: 1

Total number of chains: 2

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	2	2ETKA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2ETKA	2.96	Active	DFGin	BLAminus	in-in	in-in	HFS	Type1
AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2ETKB	2.96	Inactive	DFGin	BLAminus	in-in	in-out	HFS	Type1

Protein kinases in complex with HFS

Total number of genes: 2

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	2ERZE

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2ETKA	2.96	Active	DFGin	BLAminus	in-in	in-in	HFS	Type1
Homo sapiens	AGC	ROCK1	ROCK1_HUMAN	Rho-associated protein kinase 1	2ETKB	2.96	Inactive	DFGin	BLAminus	in-in	in-out	HFS	Type1
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	2ERZE	2.2	Active	DFGin	BLAminus	in-in	in-in	HFS	Type1

Protein kinases in complex with HFS

Total number of genes: 1

Total number of chains: 1

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	2ERZE

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Mus musculus	AGC	PRKACA	KAPCA_MOUSE	cAMP-dependent protein kinase catalytic subunit alpha	2ERZE	2.2	Active	DFGin	BLAminus	in-in	in-in	HFS	Type1