Ligand: LY4 (Ruboxistaurin)

Total number of chains: 3
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 2J2IB
DFGin None 1 33.3% 9S9TA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC PDPK1 PDPK1_HUMAN 1UU3A 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi LY4 Type1 73 - 360 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1
AGC PRKCB KPCB_HUMAN 9S9TA 3.425 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LY4 Type1 340 - 667 0 TPO500,TPO642,SEP661 D427N Protein kinase C beta type
CAMK PIM1 PIM1_HUMAN 2J2IB 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LY4 Type1 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1

Ligand: LY4 (Ruboxistaurin)

Total number of chains: 3
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 2J2IB
DFGin None 1 33.3% 9S9TA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC PDPK1 PDPK1_HUMAN 1UU3A 1.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi LY4 Type1 73 - 360 0 SEP241 None 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PRKCB KPCB_HUMAN 9S9TA 3.425 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LY4 Type1 340 - 667 0 TPO500,TPO642,SEP661 D427N Protein kinase C beta type Homo sapiens
CAMK PIM1 PIM1_HUMAN 2J2IB 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LY4 Type1 33 - 305 0 None R250G Serine/threonine-protein kinase pim-1 Homo sapiens

Ligand: LY4 (Ruboxistaurin)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism