NEK_NEK8 (Serine/threonine-protein kinase Nek8)

Total number of chains: 2
Active chains: 2
Family: NEK
Uniprot: NEK8_HUMAN
Kinase Domain Residues: 4 - 258
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q86SG6-K1A

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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q86SG6-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8
AF-Q86SG6-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8

NEK_NEK8 (Serine/threonine-protein kinase Nek8)

Total number of chains: 2
Active chains: 2
Family: NEK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q86SG6-K1A

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
NEK8_HUMAN AF-Q86SG6-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8 Homo sapiens
NEK8_HUMAN AF-Q86SG6-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 1 - 266 0 None None Serine/threonine-protein kinase Nek8 Homo sapiens

NEK_NEK8 (Serine/threonine-protein kinase Nek8)

Total number of chains: 0
Active chains: 0
Family: NEK
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism