CAMK_MELK (Maternal embryonic leucine zipper kinase)

Total number of chains: 53
Active chains: 2
Uniprot: MELK_HUMAN
Kinase Domain Residues: 11 - 263
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 41 77.4% AF-Q14680-K1A
None None 3 5.7% 6VXRA
DFGin ABAminus 2 3.8% 4BL1A
DFGin None 2 3.8% 5MAIA
DFGinter None 2 3.8% 4UMTA
DFGin BLBminus 1 1.9% 5IHCA
DFGinter BABtrans 1 1.9% 4IXPA
DFGout None 1 1.9% 5K00A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q14680-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 271 0 None None Maternal embryonic leucine zipper kinase
AF-Q14680-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 271 0 None None Maternal embryonic leucine zipper kinase
4BL1A 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 2 - 333 0 None None Maternal embryonic leucine zipper kinase
5TX3A 2.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7MY Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase
5TWUA 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni No_ligand No_ligand 1 - 333 0 None None Maternal embryonic leucine zipper kinase
5TWUB 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi No_ligand No_ligand 1 - 335 0 None None Maternal embryonic leucine zipper kinase
5TWZA 2.631 Inactive DFGin‑BLAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 45R Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase
6GVXB 2.24 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni TAK Type1 1 - 335 0 None None Maternal embryonic leucine zipper kinase
4BKZA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 1WS Type1 2 - 334 0 None None Maternal embryonic leucine zipper kinase
5M5AA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn KSA Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase
5MAGA 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 7KC Type1 3 - 335 0 None None Maternal embryonic leucine zipper kinase
5MAHA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 7KD Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase
9F31A 2.0 Inactive DFGin‑BLAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1H9M Type1 1 - 335 0 None None Maternal embryonic leucine zipper kinase
4D2TA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nooi 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2VB 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi 45R Type1 2 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2WA 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2WB 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2WD 1.92 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_nnii NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4UMRA 3.0 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo QBB Type1 6 - 333 0 None T167A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
5TVTA 2.28 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni 7LV Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase
5TWLA 2.42 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnni H91 Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase
5MAFA 2.8 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn XIN Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase
4UMPB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4UMQA 2.6 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo B5S Type1.5_Back 5 - 333 0 None T167A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
5IHCA 2.14 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6BB Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
5TWYA 2.91 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoni APEdist_nnno 7LY Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase
5MAIA 2.15 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase
4IXPA 2.749 Inactive DFGinter‑BABtrans out-none out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 2 - 335 0 None K40R,D150A Maternal embryonic leucine zipper kinase
4UMTA 1.98 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo 47W Type1 3 - 333 0 None N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4UMUA 2.02 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo 0V0 Type1 3 - 333 0 None None Maternal embryonic leucine zipper kinase
5K00A 1.77 Inactive DFGout‑None out-in out-none nonTYR APEdihe_aanii APEdist_nnnn 6PV Type2 3 - 327 0 None None Maternal embryonic leucine zipper kinase
6VXRA 2.1 Inactive None‑None out-none none-out nonTYR APEdihe_aaoii APEdist_nnno F7D Type1 1 - 332 0 None None Maternal embryonic leucine zipper kinase
5TWYB 2.91 Inactive None‑None out-none none-none nonTYR APEdihe_aannn APEdist_nnnn 7LY Type1 2 - 332 0 None None Maternal embryonic leucine zipper kinase
5TX3B 2.9 Inactive None‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnni 7MY Type1 1 - 334 0 None None Maternal embryonic leucine zipper kinase
5IH8A 1.85 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BJ Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
5IH9A 1.79 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BF Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
5IHAA 1.96 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BE Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase
6GVXA 2.24 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii TAK Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase
4BKYA 1.83 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 82B Type1 3 - 333 0 None None Maternal embryonic leucine zipper kinase
4D2TB 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnii 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2TC 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2TD 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2VA 2.45 None DFGin‑BLAminus in-in none-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2VC 2.45 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2VD 2.45 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2WC 1.92 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4UMPD 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1 2 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2PA 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2PB 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnii 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2PC 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4D2PD 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4UMPA 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase
4UMPC 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase

CAMK_MELK (Maternal embryonic leucine zipper kinase)

Total number of chains: 55
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 43 78.2% AF-Q14680-K1A
None None 3 5.5% 6VXRA
DFGin ABAminus 2 3.6% 4BL1A
DFGin None 2 3.6% 5MAIA
DFGinter None 2 3.6% 4UMTA
DFGin BLBminus 1 1.8% 5IHCA
DFGinter BABtrans 1 1.8% 4IXPA
DFGout None 1 1.8% 5K00A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MELK_HUMAN AF-Q14680-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 271 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN AF-Q14680-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 3 - 271 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4BL1A 2.6 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn ANP ATPlike 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TX3A 2.9 Inactive DFGin‑ABAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno 7MY Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TWUA 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni No_ligand No_ligand 1 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TWUB 2.603 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnoi No_ligand No_ligand 1 - 335 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TWZA 2.631 Inactive DFGin‑BLAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno 45R Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 6GVXB 2.24 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni TAK Type1 1 - 335 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4BKZA 2.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 1WS Type1 2 - 334 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5M5AA 1.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn KSA Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5MAGA 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 7KC Type1 3 - 335 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5MAHA 2.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn 7KD Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 9F31A 2.0 Inactive DFGin‑BLAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1H9M Type1 1 - 335 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2TA 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nooi 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2VB 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi 45R Type1 2 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2WA 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2WB 1.92 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2WD 1.92 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aaini APEdist_nnii NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMRA 3.0 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo QBB Type1 6 - 333 0 None T167A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TVTA 2.28 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni 7LV Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TWLA 2.42 Inactive DFGin‑BLAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnni H91 Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5MAFA 2.8 Inactive DFGin‑BLAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn XIN Type1.5_Back 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMPB 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaini APEdist_nnoi 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMQA 2.6 Inactive DFGin‑BLAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nnoo B5S Type1.5_Back 5 - 333 0 None T167A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5IHCA 2.14 Inactive DFGin‑BLBminus out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 6BB Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TWYA 2.91 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aaoni APEdist_nnno 7LY Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5MAIA 2.15 Inactive DFGin‑None out-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 5U5 Type1 2 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4IXPA 2.749 Inactive DFGinter‑BABtrans out-none out-out nonTYR APEdihe_aaoii APEdist_oooo No_ligand No_ligand 2 - 335 0 None K40R,D150A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMTA 1.98 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo 47W Type1 3 - 333 0 None N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMUA 2.02 Inactive DFGinter‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnoo 0V0 Type1 3 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5K00A 1.77 Inactive DFGout‑None out-in out-none nonTYR APEdihe_aanii APEdist_nnnn 6PV Type2 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 6VXRA 2.1 Inactive None‑None out-none none-out nonTYR APEdihe_aaoii APEdist_nnno F7D Type1 1 - 332 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TWYB 2.91 Inactive None‑None out-none none-none nonTYR APEdihe_aannn APEdist_nnnn 7LY Type1 2 - 332 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5TX3B 2.9 Inactive None‑None out-out none-out nonTYR APEdihe_aaioi APEdist_nnni 7MY Type1 1 - 334 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5IH8A 1.85 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BJ Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5IH9A 1.79 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BF Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 5IHAA 1.96 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 6BE Type1 3 - 327 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 6GVXA 2.24 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii TAK Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4BKYA 1.83 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aanii APEdist_nnnn 82B Type1 3 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2TB 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnii 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2TC 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2TD 2.7 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 3I7 Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2VA 2.45 None DFGin‑BLAminus in-in none-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2VC 2.45 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2VD 2.45 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 45R Type1 3 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2WC 1.92 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni NF5 Type1 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMPD 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1 2 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2PA 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2PB 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnii 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2PC 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4D2PD 2.55 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 6Z7 Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMPA 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_HUMAN 4UMPC 2.3 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_nnni 5QM Type1.5_Back 1 - 333 0 None T167A,S171A,N213T,V214A,M215A,Y218V,K219A Maternal embryonic leucine zipper kinase Homo sapiens
MELK_MOUSE 4BFMA 2.35 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ANP ATPlike 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
MELK_MOUSE 4CQGA 2.57 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii OT5 Type1 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus

CAMK_MELK (Maternal embryonic leucine zipper kinase)

Total number of chains: 2
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4BFMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MELK_MOUSE 4BFMA 2.35 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii ANP ATPlike 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus
MELK_MOUSE 4CQGA 2.57 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii OT5 Type1 2 - 326 0 None T167E Maternal embryonic leucine zipper kinase Mus musculus