CMGC_GSK3B (Glycogen synthase kinase-3 beta)

Total number of chains: 177
Active chains: 143
Uniprot: GSK3B_HUMAN
Kinase Domain Residues: 56 - 340
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 174 98.3% AF-P49841-K1A
DFGin ABAminus 2 1.1% 6Y9SA
DFGin None 1 0.6% 8QJIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
4NM5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 383 0 None None Glycogen synthase kinase-3 beta
4NM7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 383 0 None None Glycogen synthase kinase-3 beta
4NM3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta
1J1BA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta
1J1BB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta
1J1CA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta
1J1CB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta
8XN6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 384 0 None None Glycogen synthase kinase-3 beta
1PYXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 386 0 None None Glycogen synthase kinase-3 beta
1PYXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 383 0 None None Glycogen synthase kinase-3 beta
AF-P49841-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 348 0 None None Glycogen synthase kinase-3 beta
AF-P49841-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 348 0 None None Glycogen synthase kinase-3 beta
1GNGA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta
1GNGB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 28 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
1H8FA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 35 - 386 0 None None Glycogen synthase kinase-3 beta
1H8FB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 35 - 384 0 None None Glycogen synthase kinase-3 beta
1I09A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 25 - 384 0 None None Glycogen synthase kinase-3 beta
7U2ZA 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7C Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta
7U2ZB 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7C Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta
3F7ZB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 34O Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
3SD0B 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TSK Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
6HK3B 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G8B Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
6HK4A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G8E Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
6HK4B 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G8E Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
5F94A 2.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UO Type1 36 - 381 0 None None Glycogen synthase kinase-3 beta
5F94B 2.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UO Type1 37 - 385 0 None None Glycogen synthase kinase-3 beta
5F95A 2.525 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UP Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta
5F95B 2.525 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UP Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta
7U31A 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7I Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta
7U31B 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7I Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta
7SXJA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 34 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
7OY5A 2.57 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 39I Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
7OY5B 2.57 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 39I Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
7U33A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7R Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta
7U33B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7R Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta
7U36A 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7W Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta
7U36B 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7W Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta
2OW3A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BIM Type1 35 - 385 0 PTR216 None Glycogen synthase kinase-3 beta
2OW3B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BIM Type1 35 - 386 0 PTR216 None Glycogen synthase kinase-3 beta
3GB2A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G3B Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
6TCUA 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii N1Q Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
5T31A 2.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 35 - 381 0 PTR216 D133E Glycogen synthase kinase-3 beta
5T31B 2.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 36 - 382 0 PTR216 D133E Glycogen synthase kinase-3 beta
7Z1GA 2.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 27 - 383 0 None None Glycogen synthase kinase-3 beta
7B6FA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SZW Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta
8AUZA 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O9C Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta
8AUZB 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O9C Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta
4AFJA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SJJ Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
4AFJB 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SJJ Type1 34 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
3ZRKA 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRK Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
3ZRKB 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRK Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
3ZRLA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRL Type1 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta
3ZRLB 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRL Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
3ZRMA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRM Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
3ZRMB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRM Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
5K5NA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QH Type1 36 - 382 0 PTR216 V28G Glycogen synthase kinase-3 beta
5K5NB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QH Type1 36 - 384 0 PTR216 V28G Glycogen synthase kinase-3 beta
1R0EA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFN Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
1R0EB 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFN Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
1Q5KA 1.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TMU Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
1Q5KB 1.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TMU Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
3I4BA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z48 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
3I4BB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z48 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
3L1SA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z92 Type1 25 - 384 0 None None Glycogen synthase kinase-3 beta
3L1SB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z92 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
2JLDA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AG1 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
2JLDB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AG1 Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
3M1SB 3.134 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
3PUPA 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OS1 Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta
3PUPB 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OS1 Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
6B8JA 2.595 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65C Type1 37 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
6H0UA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FKB Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta
6H0UB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FKB Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta
6V6LA 2.19 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QQA Type1 37 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
3DU8A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 553 Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta
3DU8B 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 553 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
9FR5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE8 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
9FR5B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE8 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
9FR6A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFO Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
9FR6B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFO Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
9FR7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFJ Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
9FR7B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFJ Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
9FR8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE7 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
9FR8B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE7 Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta
9FR9A 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE6 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
9FR9B 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE6 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
9HUKB 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXL Type1 26 - 382 0 None None Glycogen synthase kinase-3 beta
9HULA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXM Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
9HULB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXM Type1 26 - 383 0 None None Glycogen synthase kinase-3 beta
9HV3A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXN Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
9HV3B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXN Type1 25 - 382 0 None None Glycogen synthase kinase-3 beta
1Q3DA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
1Q3DB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
1Q3WA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATU Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta
1Q3WB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATU Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
1Q41A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta
1Q41B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
1Q4LA 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 679 Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta
1Q4LB 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 679 Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
3Q3BA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55E Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta
3Q3BB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55E Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
4J1RA 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
4J1RB 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
4J1RC 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
4J1RD 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
5HLNA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65C Type1 34 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
5HLPA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65A Type1 36 - 382 0 PTR216,TPO277 None Glycogen synthase kinase-3 beta
5HLPB 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65A Type1 36 - 383 0 PTR216,TPO277 None Glycogen synthase kinase-3 beta
5KPKA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VK Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
5KPKB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
5KPLA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
5KPLB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
5KPMA 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VM Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
5KPMB 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VM Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
4IQ6A 3.12 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQ6 Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta
3SAYA 2.231 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OFT Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
3SAYB 2.231 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OFT Type1 35 - 382 0 PTR216 None Glycogen synthase kinase-3 beta
4PTCA 2.711 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WE Type1 36 - 381 0 None None Glycogen synthase kinase-3 beta
4PTCB 2.711 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WE Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4PTEA 2.033 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WF Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
4PTEB 2.033 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WF Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta
4PTGA 2.361 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WG Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
4PTGB 2.361 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WG Type1 37 - 385 0 None None Glycogen synthase kinase-3 beta
8DJCA 2.463 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UAU Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta
8DJCB 2.463 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UAU Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
8DJDA 2.205 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U3E Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta
8DJDB 2.205 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U3E Type1 36 - 384 0 None None Glycogen synthase kinase-3 beta
8DJEA 2.374 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U6S Type1 36 - 384 0 None None Glycogen synthase kinase-3 beta
8DJEB 2.374 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U6S Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta
8FF8A 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XV0 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta
8FF8B 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XV0 Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta
3F88A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3HT Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
3F88B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3HT Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
4ACCA 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7YG Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4ACCB 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7YG Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4ACDA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GR9 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4ACDB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GR9 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4ACGA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6LQ Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4ACGB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6LQ Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4ACHA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KDI Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
4ACHB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KDI Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
5OY4A 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4K Type1.5_Back 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta
4IQ6B 3.12 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQ6 Type1.5_Back 37 - 382 0 None None Glycogen synthase kinase-3 beta
6Y9SA 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
6Y9SB 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
4NM0A 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta
8XN6B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 26 - 386 0 None None Glycogen synthase kinase-3 beta
1I09B 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 37 - 382 0 None None Glycogen synthase kinase-3 beta
6HK7A 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii G8N Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta
7SXHA 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii D1E Type1 37 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
3F7ZA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 34O Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
3SD0A 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TSK Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
3ZDIA 2.645 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii UGJ Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
4B7TA 2.772 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii CWT Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
6HK3A 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii G8B Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
6Y9RA 2.08 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OH8 Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
1O9UA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADZ Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
9PE9A 2.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1CIF Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta
9PE9B 2.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1CIF Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta
7Z1FA 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 28 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
7Z1FB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 38 - 382 0 PTR216 None Glycogen synthase kinase-3 beta
8AV1A 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O9L Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta
8AV1B 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O9L Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta
6GN1A 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oiii F4N Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
6GN1B 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oiii F4N Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
2O5KA 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iiii HBM Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta
1UV5A 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii BRW Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
6GJOA 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii F1B Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
6GJOB 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii F1B Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta
3M1SA 3.134 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii DW1 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta
9HUKA 3.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXL Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta
4J71A 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 1JX Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
4J71B 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 1JX Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
5HLNB 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 65C Type1 37 - 383 0 PTR216 None Glycogen synthase kinase-3 beta
5OY4B 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4K Type1.5_Back 30 - 384 0 PTR216 None Glycogen synthase kinase-3 beta
8QJIA 3.02 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiii VNG Type1 36 - 381 0 PTR216 None Glycogen synthase kinase-3 beta
4DITA 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_iinn 0KD Type1 35 - 387 0 PTR216 None Glycogen synthase kinase-3 beta

CMGC_GSK3B (Glycogen synthase kinase-3 beta)

Total number of chains: 193
Active chains: 149
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 189 97.9% AF-P49841-K1A
DFGin ABAminus 3 1.6% 5AIRA
DFGin None 1 0.5% 8QJIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
GSK3B_HUMAN 4NM5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 24 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4NM7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 25 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4NM3A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1J1BA 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1J1BB 1.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1J1CA 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 35 - 388 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1J1CB 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 23 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8XN6A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1PYXA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1PYXB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ANP ATPlike 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN AF-P49841-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 348 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN AF-P49841-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 48 - 348 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1GNGA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1GNGB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 28 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1H8FA 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1H8FB 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1I09A 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 25 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U2ZA 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7C Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U2ZB 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7C Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3F7ZB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 34O Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3SD0B 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TSK Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6HK3B 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G8B Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6HK4A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G8E Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6HK4B 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G8E Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5F94A 2.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UO Type1 36 - 381 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5F94B 2.51 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UO Type1 37 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5F95A 2.525 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UP Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5F95B 2.525 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3UP Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U31A 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7I Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U31B 2.38 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7I Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7SXJA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 34 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7OY5A 2.57 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 39I Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7OY5B 2.57 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 39I Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U33A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7R Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U33B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7R Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U36A 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7W Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7U36B 2.75 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii L7W Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 2OW3A 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BIM Type1 35 - 385 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 2OW3B 2.8 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii BIM Type1 35 - 386 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3GB2A 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii G3B Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6TCUA 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii N1Q Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5T31A 2.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 35 - 381 0 PTR216 D133E Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5T31B 2.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 36 - 382 0 PTR216 D133E Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7Z1GA 2.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3NG Type1 27 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7B6FA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SZW Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8AUZA 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O9C Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8AUZB 2.66 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii O9C Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4AFJA 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SJJ Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4AFJB 1.98 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii SJJ Type1 34 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3ZRKA 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRK Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3ZRKB 2.37 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRK Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3ZRLA 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRL Type1 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3ZRLB 2.48 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRL Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3ZRMA 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRM Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3ZRMB 2.49 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ZRM Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5K5NA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QH Type1 36 - 382 0 PTR216 V28G Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5K5NB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6QH Type1 36 - 384 0 PTR216 V28G Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1R0EA 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFN Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1R0EB 2.25 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DFN Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q5KA 1.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TMU Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q5KB 1.94 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TMU Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3I4BA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z48 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3I4BB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z48 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3L1SA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z92 Type1 25 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3L1SB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Z92 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 2JLDA 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AG1 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 2JLDB 2.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii AG1 Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3M1SB 3.134 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii DW1 Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3PUPA 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OS1 Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3PUPB 2.99 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OS1 Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6B8JA 2.595 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65C Type1 37 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6H0UA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FKB Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6H0UB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii FKB Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6V6LA 2.19 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii QQA Type1 37 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3DU8A 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 553 Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3DU8B 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 553 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR5A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE8 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR5B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE8 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR6A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFO Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR6B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFO Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR7A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFJ Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR7B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IFJ Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR8A 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE7 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR8B 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE7 Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR9A 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE6 Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9FR9B 2.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IE6 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9HUKB 3.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXL Type1 26 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9HULA 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXM Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9HULB 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXM Type1 26 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9HV3A 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXN Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9HV3B 2.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXN Type1 25 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q3DA 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q3DB 2.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q3WA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATU Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q3WB 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ATU Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q41A 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q41B 2.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IXM Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q4LA 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 679 Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1Q4LB 2.77 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 679 Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3Q3BA 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55E Type1 35 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3Q3BB 2.7 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55E Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4J1RA 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4J1RB 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4J1RC 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4J1RD 2.702 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii I5R Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5HLNA 3.1 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65C Type1 34 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5HLPA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65A Type1 36 - 382 0 PTR216,TPO277 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5HLPB 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 65A Type1 36 - 383 0 PTR216,TPO277 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5KPKA 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VK Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5KPKB 2.4 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5KPLA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5KPLB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VL Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5KPMA 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VM Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5KPMB 2.69 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6VM Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4IQ6A 3.12 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQ6 Type1 37 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3SAYA 2.231 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OFT Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3SAYB 2.231 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii OFT Type1 35 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4PTCA 2.711 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WE Type1 36 - 381 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4PTCB 2.711 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WE Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4PTEA 2.033 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WF Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4PTEB 2.033 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WF Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4PTGA 2.361 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WG Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4PTGB 2.361 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 2WG Type1 37 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8DJCA 2.463 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UAU Type1 35 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8DJCB 2.463 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii UAU Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8DJDA 2.205 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U3E Type1 36 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8DJDB 2.205 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U3E Type1 36 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8DJEA 2.374 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U6S Type1 36 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8DJEB 2.374 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii U6S Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8FF8A 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XV0 Type1 36 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8FF8B 2.33 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii XV0 Type1 36 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3F88A 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3HT Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3F88B 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 3HT Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACCA 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7YG Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACCB 2.21 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 7YG Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACDA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GR9 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACDB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GR9 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACGA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6LQ Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACGB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6LQ Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACHA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KDI Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4ACHB 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii KDI Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5OY4A 3.2 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii B4K Type1.5_Back 36 - 385 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4IQ6B 3.12 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IQ6 Type1.5_Back 37 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6Y9SA 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6Y9SB 2.03 Inactive DFGin‑ABAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OHK Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4NM0A 2.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8XN6B 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ANP ATPlike 26 - 386 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1I09B 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 37 - 382 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6HK7A 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii G8N Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7SXHA 2.09 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii D1E Type1 37 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3F7ZA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 34O Type1 35 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3SD0A 2.7 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii TSK Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3ZDIA 2.645 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii UGJ Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4B7TA 2.772 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii CWT Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6HK3A 2.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii G8B Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6Y9RA 2.08 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii OH8 Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1O9UA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii ADZ Type1 35 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9PE9A 2.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1CIF Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9PE9B 2.11 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1CIF Type1 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7Z1FA 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 28 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 7Z1FB 3.0 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 3NG Type1 38 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8AV1A 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O9L Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8AV1B 2.15 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii O9L Type1 27 - 381 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6GN1A 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oiii F4N Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6GN1B 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oiii F4N Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 2O5KA 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaoii APEdist_iiii HBM Type1 35 - 384 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 1UV5A 2.8 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii BRW Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6GJOA 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii F1B Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 6GJOB 2.91 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii F1B Type1 35 - 383 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 3M1SA 3.134 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii DW1 Type1 35 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 9HUKA 3.5 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1IXL Type1 25 - 385 0 None None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4J71A 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 1JX Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4J71B 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 1JX Type1 36 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5HLNB 3.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 65C Type1 37 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 5OY4B 3.2 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii B4K Type1.5_Back 30 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 8QJIA 3.02 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiii VNG Type1 36 - 381 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_HUMAN 4DITA 2.6 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_iinn 0KD Type1 35 - 387 0 PTR216 None Glycogen synthase kinase-3 beta Homo sapiens
GSK3B_MOUSE 8VMFA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 27 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 8VMGA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 8VMEA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 4NU1A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3D 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 5AIRB 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 384 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 5AIRA 2.53 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 8VMGB 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 35 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3C 2.14 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 37 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3A 2.14 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii MRI Type1 36 - 387 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3B 2.14 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii MRI Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
A0A125YY75_TOXGG 9HVXA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1IYF Type1 46 - 384 0 PTR211 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6A 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_niio A1IYF Type1 46 - 384 0 PTR211,SEP257 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6B 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnio A1IYF Type1 46 - 384 0 PTR211 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6D 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnio A1IYF Type1 46 - 384 0 PTR211,SEP257 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6F 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_niio A1IYF Type1 46 - 384 0 PTR211 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii

CMGC_GSK3B (Glycogen synthase kinase-3 beta)

Total number of chains: 16
Active chains: 6
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 93.8% 8VMEA
DFGin ABAminus 1 6.2% 5AIRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
GSK3B_MOUSE 8VMFA 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 27 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 8VMGA 2.45 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 8VMEA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 4NU1A 2.5 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADP ATPlike 6 - 383 0 SEP9 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3D 2.14 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 36 - 382 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 5AIRB 2.53 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 22 - 384 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 5AIRA 2.53 Inactive DFGin‑ABAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 8VMGB 2.45 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 35 - 383 0 None None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3C 2.14 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 37 - 383 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3A 2.14 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii MRI Type1 36 - 387 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
GSK3B_MOUSE 6AE3B 2.14 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii MRI Type1 36 - 384 0 PTR216 None Glycogen synthase kinase-3 beta Mus musculus
A0A125YY75_TOXGG 9HVXA 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii A1IYF Type1 46 - 384 0 PTR211 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6A 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_niio A1IYF Type1 46 - 384 0 PTR211,SEP257 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6B 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooi APEdist_nnio A1IYF Type1 46 - 384 0 PTR211 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6D 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaooo APEdist_nnio A1IYF Type1 46 - 384 0 PTR211,SEP257 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii
A0A125YY75_TOXGG 9HW6F 2.9 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_niio A1IYF Type1 46 - 384 0 PTR211 None Putative cell-cycle-associated protein kinase GSK Toxoplasma gondii