Protein kinases in complex with RW6

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8BUFE
DFGin None 2 8BUFB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUFE 3.3 Active DFGin BLAminus in-in in-in RW6 Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUFB 3.3 Inactive DFGin None in-in in-in RW6 Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUFH 3.3 Inactive DFGin None in-out in-in RW6 Type1

Protein kinases in complex with RW6

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 8BUFE
DFGin None 2 8BUFB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUFE 3.3 Active DFGin BLAminus in-in in-in RW6 Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUFB 3.3 Inactive DFGin None in-in in-in RW6 Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 8BUFH 3.3 Inactive DFGin None in-out in-in RW6 Type1

Protein kinases in complex with RW6

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type