| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | 8BUHE |
| DFGin | None | 2 | 8BUHB |
| Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUHE | 3.79 | Active | DFGin | BLAminus | in-in | in-in | RR9 | Type1 |
| CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUHB | 3.79 | Inactive | DFGin | None | in-in | in-in | RR9 | Type1 |
| CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUHH | 3.79 | Inactive | DFGin | None | in-in | in-in | RR9 | Type1 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | 8BUHE |
| DFGin | None | 2 | 8BUHB |
| Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUHE | 3.79 | Active | DFGin | BLAminus | in-in | in-in | RR9 | Type1 |
| Homo sapiens | CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUHB | 3.79 | Inactive | DFGin | None | in-in | in-in | RR9 | Type1 |
| Homo sapiens | CMGC | CDK12 | CDK12_HUMAN | Cyclin-dependent kinase 12 | 8BUHH | 3.79 | Inactive | DFGin | None | in-in | in-in | RR9 | Type1 |
| Spatial | Dihedral | Chains | Representative |
|---|
| Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|