Ligand: RWE

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 66.7% 8BUKB
DFGin BLAminus 1 33.3% 8BUKE
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK12 CDK12_HUMAN 8BUKE 3.41 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RWE Type1 715 - 1039 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUKB 3.41 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RWE Type1 715 - 1040 0 TPO893 K965R Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 8BUKH 3.41 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RWE Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12

Ligand: RWE

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 66.7% 8BUKB
DFGin BLAminus 1 33.3% 8BUKE
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK12 CDK12_HUMAN 8BUKE 3.41 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RWE Type1 715 - 1039 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUKB 3.41 Inactive DFGin‑None in-in in-in nonTYR APEdihe_aaiii APEdist_iiii RWE Type1 715 - 1040 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens
CMGC CDK12 CDK12_HUMAN 8BUKH 3.41 Inactive DFGin‑None in-in in-out nonTYR APEdihe_aaioi APEdist_iiii RWE Type1 715 - 1044 0 TPO893 K965R Cyclin-dependent kinase 12 Homo sapiens

Ligand: RWE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism