Ligand

Protein kinases in complex with RC8

Total number of genes: 2

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	5	3DDPA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	6TD3B	3.46	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	6TD3E	3.46	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	6TD3H	3.46	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	3DDPA	2.7	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	3DDPC	2.7	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1

Protein kinases in complex with RC8

Total number of genes: 2

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	5	3DDPA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	6TD3B	3.46	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
Homo sapiens	CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	6TD3E	3.46	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
Homo sapiens	CMGC	CDK12	CDK12_HUMAN	Cyclin-dependent kinase 12	6TD3H	3.46	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	3DDPA	2.7	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1
Homo sapiens	CMGC	CDK2	CDK2_HUMAN	Cyclin-dependent kinase 2	3DDPC	2.7	Active	DFGin	BLAminus	in-in	in-in	RC8	Type1

Protein kinases in complex with RC8

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type