5LW1

MAPK8 (Mitogen-activated protein kinase 8)
Group: CMGC
Uniprot: MK08_HUMAN
Organism: Homo sapiens
Domain boundary: 26 - 321
Resolu: 3.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B Inactive DFGin ABAminus out-out out-out ADN Type1 8 - 362 0
E Inactive DFGin ABAminus in-out out-out ADN Type1 8 - 362 0
H Inactive DFGin ABAminus out-out out-out ADN Type1 8 - 362 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain H
         -         10         20         30 
mrgshhhhhh gsrskrdNNF YSVEIGDSTF TVLKRYQNLK 
        40         50         60         70 
PIGSGAQGIV CAAYDAILER NVAIKKLSRP FQNQTHAKRA 
        80         90        100        110 
YRELVLMKCV NHKNIIGLLN VFTPQKSLEE FQDVYIVMEL 
       120        130        140        150 
MDANLCQVIQ MELDHERMSY LLYQMLCGIK HLHSAGIIHR 
       160        170        180        190 
DLKPSNIVVK SDCTLKILDF GLARTAGTSF MMTPYVVTRY 
       200        210        220        230 
YRAPEVILGM GYKENVDLWS VGCIMGEMVC HKILFPGRDY 
       240        250        260        270 
IDQWNKVIEQ LGTPCPEFMK KLQPTVRTYV ENRPKYAGYS 
       280        290        300        310 
FEKLFPDVLF PADSEHNKLK ASQARDLLSK MLVIDASKRI 
       320        330        340        350 
SVDEALQHPY INVWYDPSEA EAPPPKIPDK QLDEREHTIE 
       360 
EWKELIYKEV MDl
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None