8X5M

MAPK8 (Mitogen-activated protein kinase 8)
Group: CMGC
Uniprot: MK08_HUMAN
Organism: Homo sapiens
Domain boundary: 26 - 321
Resolu: 2.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in out-out Y4O Type1 7 - 363 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        11         21         31         41 
srskrDNNFY SVEIGDSTFT VLKRYQNLKP IGsgaqGIVC 
        51         61         71         81 
AAYDAILERN VAIKKLSRPF QNQTHAKRAY RELVLMKCVN 
        91        101        111        121 
HKNIIGLLNV FTPQKSLEEF QDVYIVMELM DANLCQVIQM 
       131        141        151        161 
ELDHERMSYL LYQMLCGIKH LHSAGIIHRD LKPSNIVVKS 
       171        181        191        201 
DCTLKILDFG LARtagtsfm mtpyvVTRYY RAPEVILGMG 
       211        221        231        241 
YKENVDIWSV GCIMGEMIKG GVLFPGTDHI DQWNKVIEQL 
       251        261        271        281 
GTPCPEFMKK LQPTVRTYVE NRPKYAGYSF EKLFPDVLFP 
       291        301        311        321 
ADSEHNKLKA SQARDLLSKM LVIDASKRIS VDEALQHPYI 
       331        341        351        361 
NVWYDPSEAE APPPKIPDKQ LDEREHTIEE WKELIYKEVM 

DLe
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None