AF-P45983-K1

MAPK8 (Mitogen-activated protein kinase 8)
Group: CMGC
Uniprot: MK08_HUMAN
Organism: Homo sapiens
Domain boundary: 26 - 321
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 18 - 329 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        27         37         47         57 
STFTVLKRYQ NLKPIGSGAQ GIVCAAYDAI LERNVAIKKL 
        67         77         87         97 
SRPFQNQTHA KRAYRELVLM KCVNHKNIIG LLNVFTPQKS 
       107        117        127        137 
LEEFQDVYIV MELMDANLCQ VIQMELDHER MSYLLYQMLC 
       147        157        167        177 
GIKHLHSAGI IHRDLKPSNI VVKSDCTLKI LDFGLARTAG 
       187        197        207        217 
TSFMMTPYVV TRYYRAPEVI LGMGYKENVD LWSVGCIMGE 
       227        237        247        257 
MVCHKILFPG RDYIDQWNKV IEQLGTPCPE FMKKLQPTVR 
       267        277        287        297 
TYVENRPKYA GYSFEKLFPD VLFPADSEHN KLKASQARDL 
       307        317        327 
LSKMLVIDAS KRISVDEALQ HPYINVWYDP SE
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None