3PZE

MAPK8 (Mitogen-activated protein kinase 8)
Group: CMGC
Uniprot: MK08_HUMAN
Organism: Homo sapiens
Domain boundary: 26 - 321
Resolu: 2.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in none-out CFK Type1 7 - 362 9
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        16         26         36         46 
DNNFYSVEIG DSTFTVLKRY QNLKPIGSGA QGIVCAAYDA 
        56         66         76         86 
ILERNVAIKK LSRPFQNQTH AKRAYRELVL MKCVNHKNII 
        96        106        116        126 
GLLNVFTPQK SLEEFQDVYI VMELMDANLC QVIQMELDHE 
       136        146        156        166 
RMSYLLYQML CGIKHLHSAG IIHRDLKPSN IVVKSDCTLK 
       176        186        196        206 
ILDFGLarta gtSFMMTpyv VTRYYRAPEV ILGMGYKENV 
       216        226        236        246 
DLWSVGCIMG EMVCHKILFP GRDYIDQWNK VIEQLGTPCP 
       256        266        276        286 
EFMKKLQPTV RTYVENRPKY AGYSFEKLFP DVLFPADSEH 
       296        306        316        326 
NKLKASQARD LLSKMLVIDA SKRISVDEAL QHPYINVWYD 
       336        346        356 
PSEAEAPPPK IPDKQLDERE HTIEEWKELI YKEVMDle
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None