8S9F

BTK (Tyrosine-protein kinase BTK)
Group: TYR
Uniprot: BTK_MOUSE
Organism: Mus musculus
Domain boundary: 402 - 653
Resolu: 2.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGinter BABtrans out-out out-none 1N1 Type1 392 - 659 14
B Inactive DFGinter BABtrans out-out out-out 1N1 Type1 392 - 659 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       390        400        410        420 
mknapstagg gYGSWEIDPK DLTFLkELGT GQFGVVKYGK 
       430        440        450        460 
WRGQYDVAIK MIREGSMSED EFIEEAKVMM NLSHEKLVQL 
       470        480        490        500 
YGVCTKQRPI FIITEYMANG CLLNYLREMR HRFQTQQLLE 
       510        520        530        540 
MCKDVCEAME YLESKQFLHR DLAARNCLVN DQGVVKVSDF 
       550        560        570        580 
GLSRYvldde etssvgsKFP VRWSPPEVLM YSKFSSKSDI 
       590        600        610        620 
WAFGVLMWEI YSLGKMPYER FTNSETAEHI AQGLRLPRPH 
       630        640        650 
LASERVYTIM YSCWHEKADE RPSFKILLSN ILDVMDEES
Lower-case residues are disordered in structure.
Mutations: L390G,Y551E,Y617P
Phosphorylation: None