Protein kinases in complex with ADE

Total number of genes: 5
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 6 5LVMA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVMA 1.26 Active DFGin BLAminus in-in in-in ADE Type1
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 7BKNA 2.74 Active DFGin BLAminus in-in in-in ADE Type1
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 7BJEA 1.8 Active DFGin BLAminus in-in in-in ADE Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7IA 1.45 Active DFGin BLAminus in-in in-in ADE Type1
TKL ACVR2B AVR2B_HUMAN Activin receptor type-2B 2QLUA 2.0 Active DFGin BLAminus in-in in-in ADE Type1
TYR RET RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret 6NJAA 1.92 Active DFGin BLAminus in-in in-in ADE Type1

Protein kinases in complex with ADE

Total number of genes: 8
Total number of chains: 9
Spatial Dihedral Chains Representative
DFGin BLAminus 9 5LVMA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6Y05A 1.7 Active DFGin BLAminus in-in in-in ADE Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVMA 1.26 Active DFGin BLAminus in-in in-in ADE Type1
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 7BKNA 2.74 Active DFGin BLAminus in-in in-in ADE Type1
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 7BJEA 1.8 Active DFGin BLAminus in-in in-in ADE Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7IA 1.45 Active DFGin BLAminus in-in in-in ADE Type1
Homo sapiens TKL ACVR2B AVR2B_HUMAN Activin receptor type-2B 2QLUA 2.0 Active DFGin BLAminus in-in in-in ADE Type1
Homo sapiens TYR RET RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret 6NJAA 1.92 Active DFGin BLAminus in-in in-in ADE Type1
Mus musculus AGC PRKCI KPCI_MOUSE Protein kinase C iota type 4DC2A 2.4 None DFGin BLAminus in-none in-in ADE Type1
Saccharomyces cerevisiae CMGC SKY1 SKY1_YEAST Serine/threonine-protein kinase SKY1 1Q8YB 2.05 Active DFGin BLAminus in-in in-in ADE Type1

Protein kinases in complex with ADE

Total number of genes: 3
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 3 6Y05A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6Y05A 1.7 Active DFGin BLAminus in-in in-in ADE Type1
Mus musculus AGC PRKCI KPCI_MOUSE Protein kinase C iota type 4DC2A 2.4 None DFGin BLAminus in-none in-in ADE Type1
Saccharomyces cerevisiae CMGC SKY1 SKY1_YEAST Serine/threonine-protein kinase SKY1 1Q8YB 2.05 Active DFGin BLAminus in-in in-in ADE Type1