5X2A

EGFR (Epidermal growth factor receptor)
Group: TYR
Uniprot: EGFR_HUMAN
Organism: Homo sapiens
Domain boundary: 712 - 970
Resolu: 1.85

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Allosteric 700 - 1011 13
B Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Type1 700 - 1022 0
C Inactive DFGin BLBtrans out-out out-out 7XO Type1 700 - 1015 13
D Inactive DFGin BLBplus out-out out-out ANP Type1 701 - 1014 10
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       701        711        721        731 
gstsgeapnQ ALLRILKETE FKKIKVLGSG AFGTVYKGLW 
       741        751        761        771 
IPEGEKVKIP VAIKELREat sPKANKEILD EAYVMASVDN 
       781        791        801        811 
PHVCRLLGIC LTSTVQLIMQ LMPFGCLLDY VREHKDNIGS 
       821        831        841        851 
QYLLNWCVQI AKGMNYLEDR RLVHRDLAAR NVLVKTPQHV 
       861        871        881        891 
KITDFGLAKL LGAeekeyha eggKVPIKWM ALESILHRIY 
       901        911        921        931 
THQSDVWSYG VTVWELMTFG SKPYDGIPAS EISSILEKGE 
       941        951        961        971 
RLPQPPICTI DVYMIMRKCW MIDADSRPKF RELIIEFSKM 
       981        991       1001       1011 
ARDPQRYLVI QGDERMHLPS PTDSNFYRAL MDEEdmddVV 
      1021 
DADeylipqq g
Lower-case residues are disordered in structure.
Mutations: T790M,V948R
Phosphorylation: None