2ITV

EGFR (Epidermal growth factor receptor)
Group: TYR
Uniprot: EGFR_HUMAN
Organism: Homo sapiens
Domain boundary: 712 - 970
Resolu: 2.47

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ANP Type1 696 - 1019 9
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       705        715        725        735 
GEAPNQALLR ILKETEFKKI KVLGSGAFGT VYKGLWIPEG 
       745        755        765        775 
EKVKIPVAIK ELREATSPKA NKEILDEAYV MASVDNPHVC 
       785        795        805        815 
RLLGICLTST VQLITQLMPF GCLLDYVREH KDNIGSQYLL 
       825        835        845        855 
NWCVQIAKGM NYLEDRRLVH RDLAARNVLV KTPQHVKITD 
       865        875        885        895 
FGRAKLLGAE Ekeyhaeggk VPIKWMALES ILHRIYTHQS 
       905        915        925        935 
DVWSYGVTVW ELMTFGSKPY DGIPASEISS ILEKGERLPQ 
       945        955        965        975 
PPICTIDVYM IMVKCWMIDA DSRPKFRELI IEFSKMARDP 
       985        995       1005       1015 
QRYLVIQGDE RMHLpsptds nfyralMDEE DMDDVVDADE 

YLIPqqg
Lower-case residues are disordered in structure.
Mutations: L858R
Phosphorylation: None