Protein kinases in complex with 2K2 (Midostaurin)

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAminus 4 4NCTA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTA 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTB 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTC 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTD 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1

Protein kinases in complex with 2K2

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAminus 4 4NCTA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTA 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTB 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTC 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 4NCTD 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1

Protein kinases in complex with 2K2

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type