6LN1

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)
Group: CMGC
Uniprot: DYR1A_HUMAN
Organism: Homo sapiens
Domain boundary: 159 - 479
Resolu: 2.699

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in EKU Type1 135 - 480 0
B Active DFGin BLAminus in-in in-in EKU Type1 140 - 479 4
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       144        154        164        174 
vyndgYDDDN YDYIVKNGEK WMDRYEIDSL IGKGSFGQVV 
       184        194        204        214 
KAYDRVEQEW VAIKIIKNKK AFLNQAQIEV RLLELMNKHd 
       224        234        244        254 
TEMKYYIVHL KRHFMFRNHL CLVFEMLSYN LYDLLRNTNF 
       264        274        284        294 
RGVSLNLTRK FAQQMCTALL FLATPELSII HCDLKPENIL 
       304        314        324        334 
LCNPKRSAIK IVDFGSSCQL gqriYQYIQS RFYRSPEVLL 
       344        354        364        374 
GMPYDLAIDM WSLGCILVEM HTGEPLFSGA NEVDQMNKIV 
       384        394        404          - 
EVLGIPPAHI LDQAPKARKF FEKLPDGTWN LKKtkdgkRF 
       423        433        443        453 
EYKPPGTRKL HNILGVETGG PGGRRAGESG HTVADYLKFK 
       463        473 
DLILRMLDYD PKTRIQPYYA LQHSFFk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X321