6A1G

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)
Group: CMGC
Uniprot: DYR1A_HUMAN
Organism: Homo sapiens
Domain boundary: 159 - 479
Resolu: 2.15

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 9OL Type1 134 - 480 0
B Active DFGin BLAminus in-in in-in 9OL Type1 135 - 480 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       133        143        153        163 
gpmsshkker kVYNDGYDDD NYDYIVKNGE KWMDRYEIDS 
       173        183        193        203 
LIGKGSFGQV VKAYDRVEQE WVAIKIIKNK KAFLNQAQIE 
       213        223        233        243 
VRLLELMNKH DTEMKYYIVH LKRHFMFRNH LCLVFEMLSY 
       253        263        273        283 
NLYDLLRNTN FRGVSLNLTR KFAQQMCTAL LFLATPELSI 
       293        303        313        323 
IHCDLKPENI LLCNPKRSAI KIVDFGSSCQ LGQRIYQYIQ 
       333        343        353        363 
SRFYRSPEVL LGMPYDLAID MWSLGCILVE MHTGEPLFSG 
       373        383        393        403 
ANEVDQMNKI VEVLGIPPAH ILDQAPKARK FFEKLPDGTW 
       413        423        433        443 
NLKktkdgkr eYKPPGTRKL HNILGVETGG PGGRRAGESG 
       453        463        473        483 
HTVADYLKFK DLILRMLDYD PKTRIQPYYA LQHSFFKkta


Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X321