AF-Q13627-K1

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)
Group: CMGC
Uniprot: DYR1A_HUMAN
Organism: Homo sapiens
Domain boundary: 159 - 479
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 151 - 487 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       160        170        180        190 
NGEKWMDRYE IDSLIGKGSF GQVVKAYDRV EQEWVAIKII 
       200        210        220        230 
KNKKAFLNQA QIEVRLLELM NKHDTEMKYY IVHLKRHFMF 
       240        250        260        270 
RNHLCLVFEM LSYNLYDLLR NTNFRGVSLN LTRKFAQQMC 
       280        290        300        310 
TALLFLATPE LSIIHCDLKP ENILLCNPKR SAIKIVDFGS 
       320        330        340        350 
SCQLGQRIYQ YIQSRFYRSP EVLLGMPYDL AIDMWSLGCI 
       360        370        380        390 
LVEMHTGEPL FSGANEVDQM NKIVEVLGIP PAHILDQAPK 
       400        410        420        430 
ARKFFEKLPD GTWNLKKTKD GKREYKPPGT RKLHNILGVE 
       440        450        460        470 
TGGPGGRRAG ESGHTVADYL KFKDLILRML DYDPKTRIQP 
       480 
YYALQHSFFK KTADEGT
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None