4NCT

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)
Group: CMGC
Uniprot: DYR1A_HUMAN
Organism: Homo sapiens
Domain boundary: 159 - 479
Resolu: 2.597

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 480 0
B Active DFGin BLAminus in-in in-in 2K2 Type1 133 - 480 0
C Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 479 0
D Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 480 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       132        142        152        162 
gasdsshkke rKVYNDGYDD DNYDYIVKNG EKWMDRYEID 
       172        182        192        202 
SLIGKGSFGQ VVKAYDRVEQ EWVAIKIIKN KKAFLNQAQI 
       212        222        232        242 
EVRLLELMNK HDTEMKYYIV HLKRHFMFRN HLCLVFEMLS 
       252        262        272        282 
YNLYDLLRNT NFRGVSLNLT RKFAQQMCTA LLFLATPELS 
       292        302        312        322 
IIHCDLKPEN ILLCNPKRSA IKIVDFGSSC QLGQRIYQYI 
       332        342        352        362 
QSRFYRSPEV LLGMPYDLAI DMWSLGCILV EMHTGEPLFS 
       372        382        392        402 
GANEVDQMNK IVEVLGIPPA HILDQAPKAR KFFEKLPDGT 
       412        422        432        442 
WNLKKtkdgk reYKPPGTRK LHNILGVETG GPGGrrages 
       452        462        472        482 
ghTVADYLKF KDLILRMLDY DPKTRIQPYY ALQHSFFKkt 

adegtnts
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X321