7AJ2

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)
Group: CMGC
Uniprot: DYR1A_HUMAN
Organism: Homo sapiens
Domain boundary: 159 - 479
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in RJ5 Type1 148 - 481 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -        156        166 
mgsshhhhhh ssglvprgsh mIVKNGEKWM DRYEIDSLIG 
       176        186        196        206 
KGSFGQVVKA YDRVEQEWVA IKIIKNKKAF LNQAQIEVRL 
       216        226        236        246 
LELMNKHDTE MKYYIVHLKR HFMFRNHLCL VFEMLSYNLY 
       256        266        276        286 
DLLRNTNFRG VSLNLTRKFA QQMCTALLFL ATPELSIIHC 
       296        306        316        326 
DLKPENILLC NPKRSAIKIV DFGSSCQLGQ RIYQYIQSRF 
       336        346        356        366 
YRSPEVLLGM PYDLAIDMWS LGCILVEMHT GEPLFSGANE 
       376        386        396        406 
VDQMNKIVEV LGIPPAHILD QAPKARKFFE KLPDGTWNLK 
       416        426        436        446 
KTKDgkreYK PPGTRKLHNI LGVETGGPGG RRAGESGHTV 
       456        466        476 
ADYLKFKDLI LRMLDYDPKT RIQPYYALQH SFFKKtade
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X321