Ligand: 4H5

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 4 4YU2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 134 - 482 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 134 - 481 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 135 - 481 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 135 - 481 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: 4H5

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 4 4YU2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 134 - 482 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 134 - 481 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 135 - 481 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 4YU2 2.9 Active DFGin‑BLAminus in-in in-in 4H5 Type1 135 - 481 0 X321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens

Ligand: 4H5

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism