8W38

FGFR2 (Fibroblast growth factor receptor 2)
Group: TYR
Uniprot: FGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 481 - 759
Resolu: 2.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 0
B Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 6
C Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 465 - 764 11
D Active DFGin BLAminus in-in in-in TZ0 Type1.5_Back 467 - 764 11
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
         -        464        474        484 
mgsshhhhhh sqdpmlagvs eyELPEDPKW EFPRDKLTLG 
       494        504        514        524 
KPLGEGCFGQ VVMAEAVGId kdkpKEAVTV AVKMLKDDAT 
       534        544        554        564 
EKDLSDLVSE MEMMKMIGKH KNIIDLLGAC TQDGPLYVIV 
       574        584        594        604 
EYASKGNLRE YLRARRppgm eysydinRVP EEQMTFKDLV 
       614        624        634        644 
SCTYQLARGM EYLASQKCIH RDLAARNVLV TENNVMKIAD 
       654        664        674        684 
FGLARVInni dyykkttnGR LPVKWMAPEA LFDRVYTHQS 
       694        704        714        724 
DVWSFGVLMW EIFTLGGSPY PGIPVEELFK LLKEGHRMDK 
       734        744        754        764 
PANCTNELYM MMRDCWHAVP SQRPTFKQLV EDLDRILTLT 

tnee
Lower-case residues are disordered in structure.
Mutations: N549D,D650V
Phosphorylation: None