TYR_FGFR1 (Fibroblast growth factor receptor 1)

Total number of chains: 145
Active chains: 3
Uniprot: FGFR1_HUMAN
Kinase Domain Residues: 478 - 756
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 114 78.6% 9UHIA
DFGin BLBplus 11 7.6% 8JQIB
DFGin BLAminus 10 6.9% AF-P11362-K1A
DFGin None 5 3.4% 4NKAB
DFGout None 3 2.1% 4V04A
DFGin BLBminus 1 0.7% 3KXXA
DFGout BBAminus 1 0.7% 4V04B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
3GQIA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 464 - 770 0 PTR653,PTR654,PTR766 C488A,Y583F,C584S,Y585F Fibroblast growth factor receptor 1
AF-P11362-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 470 - 764 0 None None Fibroblast growth factor receptor 1
AF-P11362-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 470 - 764 0 None None Fibroblast growth factor receptor 1
3KXXB 3.2 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 460 - 764 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
3KXXC 3.2 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 458 - 762 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
3KXXD 3.2 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 458 - 762 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
5FLFA 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 460 - 762 0 None R675G Fibroblast growth factor receptor 1
5FLFB 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 460 - 764 0 None R675G Fibroblast growth factor receptor 1
5FLFC 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 464 - 763 0 None R675G Fibroblast growth factor receptor 1
5FLFD 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 465 - 763 0 None R675G Fibroblast growth factor receptor 1
4RWIA 2.292 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
4RWIB 2.292 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
1FGKA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 464 - 762 0 None None Fibroblast growth factor receptor 1
1FGKB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 761 0 None C488A Fibroblast growth factor receptor 1
4UWYA 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 462 - 762 0 None None Fibroblast growth factor receptor 1
4UWYB 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao No_ligand No_ligand 459 - 762 0 None None Fibroblast growth factor receptor 1
3KY2A 2.7 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
3KY2B 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
4RWLA 2.193 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
5FLFE 2.58 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iooai APEdist_aaao No_ligand No_ligand 466 - 761 0 None R675G Fibroblast growth factor receptor 1
5AM7A 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 764 0 None V561M Fibroblast growth factor receptor 1
5AM7B 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None V561M Fibroblast growth factor receptor 1
4RWKA 2.982 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1 458 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
4ZSAA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4ZSAB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 462 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
5Z0SA 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
5Z0SB 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
6ITJA 1.994 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao AXU Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
6ITJB 1.994 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao AXU Type1 459 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
9CD5A 2.939 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 465 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
9CD5B 2.939 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
4F63A 2.55 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
4F63B 2.55 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
4F64A 2.05 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
4F64B 2.05 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
4NKAA 2.19 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 2K7 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4NKSA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 465 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
4NKSB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
4UWBA 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4UWBB 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 459 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4UWCA 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4UWCB 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 459 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
5O49A 1.91 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
5O49B 1.91 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
5O4AA 2.01 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 464 - 764 0 None None Fibroblast growth factor receptor 1
5O4AB 2.01 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1
7OZBAAA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
7OZBBBB 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
7OZDAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
7OZDBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
7OZFAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 465 - 765 0 None None Fibroblast growth factor receptor 1
7OZFBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1
1AGWA 2.4 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 464 - 762 0 None None Fibroblast growth factor receptor 1
1AGWB 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
1FGIA 2.5 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1
1FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
5AM6A 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 765 0 None None Fibroblast growth factor receptor 1
5AM6B 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None None Fibroblast growth factor receptor 1
5UQ0A 2.3 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
5UQ0B 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
3JS2A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
3JS2B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 459 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
3GQLC 2.8 Inactive DFGin‑BLAplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 766 0 None C488A Fibroblast growth factor receptor 1
8JMZA 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 460 - 765 0 None C584S Fibroblast growth factor receptor 1
8JMZB 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 458 - 763 0 None C584S Fibroblast growth factor receptor 1
9UHCA 1.88 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
9UHCB 1.88 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
9UHIA 1.76 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 764 0 None None Fibroblast growth factor receptor 1
9UHIB 1.76 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 763 0 None None Fibroblast growth factor receptor 1
5A46A 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 464 - 766 0 None None Fibroblast growth factor receptor 1
5A46B 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 766 0 None None Fibroblast growth factor receptor 1
4RWKB 2.982 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1
3C4FA 2.07 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
3C4FB 2.07 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1
3RHXA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
3RHXB 2.01 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1
5A4CA 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
5A4CB 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 461 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4NK9B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4V05A 2.57 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
4V05B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 764 0 None None Fibroblast growth factor receptor 1
5EW8A 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
5EW8B 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 461 - 765 0 None None Fibroblast growth factor receptor 1
2FGIA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 464 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
2FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 461 - 761 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
5B7VA 2.15 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 464 - 763 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
4WUNA 1.65 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 66T Type1.5_Back 465 - 765 0 None None Fibroblast growth factor receptor 1
4WUNB 1.65 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 66T Type1.5_Back 461 - 762 0 None None Fibroblast growth factor receptor 1
5UR1A 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
6C18A 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY5 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
6C19A 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
6C19B 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 762 0 None None Fibroblast growth factor receptor 1
6C1BA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY4 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
6C1BB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY4 Type1.5_Back 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
6C1CA 2.15 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY6 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
6C1CB 2.15 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY6 Type1.5_Back 463 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
6C1OA 2.29 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao MK9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
6C1OB 2.29 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan MK9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
6MZQA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
6MZQB 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 462 - 761 0 None None Fibroblast growth factor receptor 1
4RWJA 2.489 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
4RWJB 2.489 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
3GQLA 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oooai APEdist_aaao GQL Type1.5_Back 463 - 774 0 None C488A Fibroblast growth factor receptor 1
3TT0A 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 07J Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
3TT0B 2.8 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnnao APEdist_aaan 07J Type1.5_Back 459 - 763 0 None C584S Fibroblast growth factor receptor 1
8Y22A 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 459 - 762 0 None C584S Fibroblast growth factor receptor 1
8Y22B 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
6NVLA 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1
6NVLB 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1
6NVLC 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1
6NVLD 2.7 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1
7WCLA 2.495 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 459 - 764 0 None C584S Fibroblast growth factor receptor 1
7WCLB 2.495 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
8XLOA 2.36 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 462 - 764 0 None C584S Fibroblast growth factor receptor 1
8XLOB 2.36 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1
8XZ7B 1.75 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1
6MZWA 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1
5VNDA 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 463 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
5VNDB 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 460 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1
6P68A 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
6P68B 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
6P68C 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 463 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1
6P69A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 462 - 765 0 None C488A,Y563C Fibroblast growth factor receptor 1
6P69B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 461 - 762 0 None C488A,Y563C Fibroblast growth factor receptor 1
3KXXA 3.2 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 461 - 765 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1
8JQIB 4.1 Inactive DFGin‑BLBplus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 463 - 769 0 None None Fibroblast growth factor receptor 1
8YKIA 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1
8YKIB 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1
3GQLB 2.8 Inactive DFGin‑BLBplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 765 0 None C488A Fibroblast growth factor receptor 1
8XZ7A 1.75 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1 458 - 765 0 None C584S Fibroblast growth factor receptor 1
5ZV2A 2.86 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LEV Type1.5_Back 463 - 762 0 None C488A Fibroblast growth factor receptor 1
5ZV2B 2.86 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nioai APEdist_aaao LEV Type1.5_Back 461 - 764 0 None C488A Fibroblast growth factor receptor 1
4NK9A 2.57 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
5B7VB 2.15 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 462 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1
5UR1B 2.2 Inactive DFGin‑BLBplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
4RWLB 2.193 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3ZC Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1
4F65A 2.26 Inactive DFGin‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0S9 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4NKAB 2.19 Inactive DFGin‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 2K7 Type1 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4F65B 2.26 Inactive DFGin‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0S9 Type1.5_Back 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
6C18B 2.3 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan YY5 Type1.5_Back 466 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1
6MZWB 2.2 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 463 - 762 0 None None Fibroblast growth factor receptor 1
4V04B 2.12 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4V01A 2.33 Inactive DFGout‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
4V01B 2.33 Inactive DFGout‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 461 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1
4V04A 2.12 Inactive DFGout‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 463 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1

TYR_FGFR1 (Fibroblast growth factor receptor 1)

Total number of chains: 145
Active chains: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 114 78.6% 9UHIA
DFGin BLBplus 11 7.6% 8JQIB
DFGin BLAminus 10 6.9% AF-P11362-K1A
DFGin None 5 3.4% 4NKAB
DFGout None 3 2.1% 4V04A
DFGin BLBminus 1 0.7% 3KXXA
DFGout BBAminus 1 0.7% 4V04B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
FGFR1_HUMAN 3GQIA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ACP ATPlike 464 - 770 0 PTR653,PTR654,PTR766 C488A,Y583F,C584S,Y585F Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN AF-P11362-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 470 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN AF-P11362-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 470 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3KXXB 3.2 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 460 - 764 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3KXXC 3.2 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 458 - 762 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3KXXD 3.2 Inactive DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 458 - 762 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5FLFA 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 460 - 762 0 None R675G Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5FLFB 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 460 - 764 0 None R675G Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5FLFC 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 464 - 763 0 None R675G Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5FLFD 2.58 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 465 - 763 0 None R675G Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWIA 2.292 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWIB 2.292 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 1FGKA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 464 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 1FGKB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4UWYA 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 462 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4UWYB 2.305 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_nnoai APEdist_aaao No_ligand No_ligand 459 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3KY2A 2.7 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3KY2B 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWLA 2.193 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao No_ligand No_ligand 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5FLFE 2.58 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iooai APEdist_aaao No_ligand No_ligand 466 - 761 0 None R675G Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5AM7A 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 764 0 None V561M Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5AM7B 1.957 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None V561M Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWKA 2.982 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1 458 - 764 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4ZSAA 2.0 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4ZSAB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 4UT Type1 462 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5Z0SA 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5Z0SB 2.45 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 960 Type1 464 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6ITJA 1.994 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao AXU Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6ITJB 1.994 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao AXU Type1 459 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 9CD5A 2.939 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 465 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 9CD5B 2.939 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1AV2 Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4F63A 2.55 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4F63B 2.55 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 0S7 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4F64A 2.05 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 464 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4F64B 2.05 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 0S8 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4NKAA 2.19 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao 2K7 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4NKSA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 465 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4NKSB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2M2 Type1 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4UWBA 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4UWBB 2.31 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao JVT Type1 459 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4UWCA 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4UWCB 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 4Y0 Type1 459 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5O49A 1.91 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5O49B 1.91 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K5 Type1 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5O4AA 2.01 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 464 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5O4AB 2.01 Inactive DFGin‑BLAplus in-out none-out TYR APEdihe_iioai APEdist_aaao 9K8 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7OZBAAA 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7OZBBBB 1.71 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 47I Type1 460 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7OZDAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7OZDBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 42I Type1 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7OZFAAA 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 465 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7OZFBBB 1.82 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 466 Type1 460 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 1AGWA 2.4 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 464 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 1AGWB 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU2 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 1FGIA 2.5 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 1FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao SU1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5AM6A 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5AM6B 1.96 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5UQ0A 2.3 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5UQ0B 2.3 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao WP1 Type1 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3JS2A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3JS2B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao VM1 Type1 459 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3GQLC 2.8 Inactive DFGin‑BLAplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 766 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8JMZA 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 460 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8JMZB 1.988 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao UKI Type1 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 9UHCA 1.88 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 9UHCB 1.88 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPE Type1 458 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 9UHIA 1.76 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 9UHIB 1.76 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1EPF Type1 458 - 763 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5A46A 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 464 - 766 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5A46B 2.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 38O Type1 458 - 766 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWKB 2.982 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,V561M,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3C4FA 2.07 Inactive DFGin‑BLAplus in-out out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3C4FB 2.07 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao C4F Type1.5_Back 464 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3RHXA 2.01 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 464 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3RHXB 2.01 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3RH Type1.5_Back 461 - 761 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5A4CA 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5A4CB 2.09 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XOJ Type1.5_Back 461 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4NK9B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 460 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4V05A 2.57 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4V05B 2.57 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 764 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5EW8A 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5EW8B 1.63 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 5SF Type1.5_Back 461 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 2FGIA 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 464 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 2FGIB 2.5 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao PD1 Type1.5_Back 461 - 761 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5B7VA 2.15 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 464 - 763 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4WUNA 1.65 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan 66T Type1.5_Back 465 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4WUNB 1.65 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 66T Type1.5_Back 461 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5UR1A 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C18A 2.3 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY5 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C19A 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C19B 2.12 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY7 Type1.5_Back 464 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C1BA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY4 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C1BB 2.0 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY4 Type1.5_Back 463 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C1CA 2.15 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY6 Type1.5_Back 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C1CB 2.15 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao YY6 Type1.5_Back 463 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C1OA 2.29 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao MK9 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C1OB 2.29 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan MK9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6MZQA 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6MZQB 2.0 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 462 - 761 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWJA 2.489 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWJB 2.489 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 66T Type1.5_Back 459 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3GQLA 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_oooai APEdist_aaao GQL Type1.5_Back 463 - 774 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3TT0A 2.8 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 07J Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3TT0B 2.8 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnnao APEdist_aaan 07J Type1.5_Back 459 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8Y22A 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 459 - 762 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8Y22B 2.792 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LW9 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6NVLA 2.7 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 463 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6NVLB 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 461 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6NVLC 2.7 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan XL6 Type1.5_Back 465 - 761 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6NVLD 2.7 Inactive DFGin‑BLAplus in-none none-out TYR APEdihe_iioai APEdist_aaao XL6 Type1.5_Back 471 - 762 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7WCLA 2.495 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 459 - 764 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 7WCLB 2.495 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao 8ZF Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8XLOA 2.36 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 462 - 764 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8XLOB 2.36 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LVQ Type1.5_Back 458 - 763 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8XZ7B 1.75 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1.5_Back 461 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6MZWA 2.2 Inactive DFGin‑BLAplus in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 464 - 765 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5VNDA 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 463 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5VNDB 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao 9ES Type1.5_Back 460 - 765 0 None C488A,Y563C,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6P68A 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6P68B 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 462 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6P68C 2.9 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O1Y Type1.5_Back 463 - 763 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6P69A 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 462 - 765 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6P69B 2.2 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao O21 Type1.5_Back 461 - 762 0 None C488A,Y563C Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3KXXA 3.2 Inactive DFGin‑BLBminus in-in in-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 461 - 765 0 None C488A,R577E,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8JQIB 4.1 Inactive DFGin‑BLBplus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 463 - 769 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8YKIA 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 464 - 762 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8YKIB 2.79 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nnoai APEdist_aaao A1LY1 Type1 461 - 761 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 3GQLB 2.8 Inactive DFGin‑BLBplus in-in out-none TYR APEdihe_nnnai APEdist_aaan GQL Type1 463 - 765 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 8XZ7A 1.75 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao A1LWW Type1 458 - 765 0 None C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5ZV2A 2.86 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LEV Type1.5_Back 463 - 762 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5ZV2B 2.86 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_nioai APEdist_aaao LEV Type1.5_Back 461 - 764 0 None C488A Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4NK9A 2.57 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 2K5 Type1.5_Back 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5B7VB 2.15 Inactive DFGin‑BLBplus in-in out-out TYR APEdihe_iioai APEdist_aaao LWJ Type1.5_Back 462 - 762 0 None L457V,C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 5UR1B 2.2 Inactive DFGin‑BLBplus in-in none-none TYR APEdihe_nnnai APEdist_aaan YY9 Type1.5_Back 464 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4RWLB 2.193 Inactive DFGin‑BLBplus in-in none-out TYR APEdihe_iioai APEdist_aaao 3ZC Type1.5_Back 458 - 764 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4F65A 2.26 Inactive DFGin‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0S9 Type1 464 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4NKAB 2.19 Inactive DFGin‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 2K7 Type1 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4F65B 2.26 Inactive DFGin‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0S9 Type1.5_Back 460 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6C18B 2.3 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan YY5 Type1.5_Back 466 - 762 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 6MZWB 2.2 Inactive DFGin‑None in-in none-none TYR APEdihe_nnnai APEdist_aaan TZ0 Type1.5_Back 463 - 762 0 None None Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4V04B 2.12 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4V01A 2.33 Inactive DFGout‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 465 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4V01B 2.33 Inactive DFGout‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 461 - 763 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
FGFR1_HUMAN 4V04A 2.12 Inactive DFGout‑None in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 463 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens

TYR_FGFR1 (Fibroblast growth factor receptor 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism