Ligand: PP2

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 1QPEA
DFGinter BABtrans 1 50.0% 3SXSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR BMX BMX_HUMAN 3SXSA 1.89 Inactive DFGinter‑BABtrans out-out in-in TYR APEdihe_iiiai APEdist_aaai PP2 Type1 411 - 671 0 None Q432K,Q611M,D617T,Q620E Cytoplasmic tyrosine-protein kinase BMX
TYR LCK LCK_HUMAN 1QPEA 2.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai PP2 Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck

Ligand: PP2

Total number of chains: 7
Active chains: 1
Total number of genes: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 85.7% 1QPEA
DFGinter BABtrans 1 14.3% 3SXSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 3GEQA 2.2 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan PP2 Type1 251 - 533 0 None R388A Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3GEQB 2.2 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan PP2 Type1 251 - 533 0 None R388A Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR BMX BMX_HUMAN 3SXSA 1.89 Inactive DFGinter‑BABtrans out-out in-in TYR APEdihe_iiiai APEdist_aaai PP2 Type1 411 - 671 0 None Q432K,Q611M,D617T,Q620E Cytoplasmic tyrosine-protein kinase BMX Homo sapiens
TYR LCK LCK_HUMAN 1QPEA 2.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai PP2 Type1 231 - 501 0 PTR394 None Tyrosine-protein kinase Lck Homo sapiens
TKL RIPK3 RIPK3_MOUSE 9IX1A 2.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1B 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TYR LYN LYN_MOUSE 2ZV9A 2.76 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP2 Type1 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus

Ligand: PP2

Total number of chains: 5
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 2ZV9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 3GEQA 2.2 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan PP2 Type1 251 - 533 0 None R388A Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3GEQB 2.2 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan PP2 Type1 251 - 533 0 None R388A Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TKL RIPK3 RIPK3_MOUSE 9IX1A 2.31 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 9IX1B 2.31 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoi APEdist_nnnn PP2 Type1 15 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TYR LYN LYN_MOUSE 2ZV9A 2.76 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP2 Type1 239 - 501 0 None None Tyrosine-protein kinase Lyn Mus musculus