Protein kinases in complex with 919 (Rebastinib)

Total number of genes: 5
Total number of chains: 11
Spatial Dihedral Chains Representative
DFGout BBAminus 9 3QRJB
DFGout None 2 5G6VB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 5G6VA 2.2 Inactive DFGout BBAminus in-in out-out 919 Type2
CMGC CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 5G6VB 2.2 Inactive DFGout None in-in out-out 919 Type2
CMGC PRPF4B PRP4B_HUMAN Serine/threonine-protein kinase PRP4 homolog 6CNHA 2.0 Inactive DFGout None in-in none-out 919 Type2
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8U8BA 3.7 Inactive DFGout BBAminus in-out none-out 919 Type2
TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8U8BB 3.7 Inactive DFGout BBAminus in-out none-out 919 Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRJA 1.82 Inactive DFGout BBAminus in-in out-in 919 Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRJB 1.82 Inactive DFGout BBAminus in-in out-in 919 Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRIA 2.1 Inactive DFGout BBAminus in-in out-in 919 Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRIB 2.1 Inactive DFGout BBAminus in-in out-in 919 Type2
TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 6MWEA 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2
TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 6MWEB 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2

Protein kinases in complex with 919

Total number of genes: 5
Total number of chains: 11
Spatial Dihedral Chains Representative
DFGout BBAminus 9 3QRJB
DFGout None 2 5G6VB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 5G6VA 2.2 Inactive DFGout BBAminus in-in out-out 919 Type2
Homo sapiens CMGC CDK16 CDK16_HUMAN Cyclin-dependent kinase 16 5G6VB 2.2 Inactive DFGout None in-in out-out 919 Type2
Homo sapiens CMGC PRPF4B PRP4B_HUMAN Serine/threonine-protein kinase PRP4 homolog 6CNHA 2.0 Inactive DFGout None in-in none-out 919 Type2
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8U8BA 3.7 Inactive DFGout BBAminus in-out none-out 919 Type2
Homo sapiens TKL LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8U8BB 3.7 Inactive DFGout BBAminus in-out none-out 919 Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRJA 1.82 Inactive DFGout BBAminus in-in out-in 919 Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRJB 1.82 Inactive DFGout BBAminus in-in out-in 919 Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRIA 2.1 Inactive DFGout BBAminus in-in out-in 919 Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRIB 2.1 Inactive DFGout BBAminus in-in out-in 919 Type2
Homo sapiens TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 6MWEA 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2
Homo sapiens TYR TEK TIE2_HUMAN Angiopoietin-1 receptor 6MWEB 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2

Protein kinases in complex with 919

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type