5G6V

CDK16 (Cyclin-dependent kinase 16)
Group: CMGC
Uniprot: CDK16_HUMAN
Organism: Homo sapiens
Domain boundary: 165 - 446
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-out 919 Type2 163 - 474 5
B Inactive DFGout None in-in out-out 919 Type2 163 - 475 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       171        181        191        201 
METYIKLDKL GEGTYATVYK GKSKLTDNLV ALKEIRLEHE 
       211        221        231        241 
EGAPCTAIRE VSLLKDLKHA NIVTLHDIIH TEKSLTLVFE 
       251        261        271        281 
YLDKDLKQYL DDCGNIINMH NVKLFLFQLL RGLAYCHRQK 
       291        301        311        321 
VLHRDLKPQN LLINERGELK LADFGLARAk siptktydne 
       331        341        351        361 
vVTLWYRPPD ILLGSTDYST QIDMWGVGCI FYEMATGRPL 
       371        381        391        401 
FPGSTVEEQL HFIFRILGTP TEETWPGILS NEEFKTYNYP 
       411        421        431        441 
KYRAEALLSH APRLDSDGAD LLTKLLQFEG RNRISAEDAM 
       451        461        471          - 
KHPFFLSLGE RIHKLPDTTS IFALKEIQLQ KEASlrsahh 

hhhh
Lower-case residues are disordered in structure.
Mutations: S319D
Phosphorylation: None