CDK16 (Cyclin-dependent kinase 16)

Group: CMGC

Uniprot: CDK16_HUMAN

Domain boundary: 165 - 446

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q00536-K1A
DFGout	BBAminus	1	5G6VA
DFGout	None	2	5G6VB

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-Q00536-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	157 - 454	None	None	0
5G6VA	2.2	Inactive	DFGout	BBAminus	in-in	out-out	919	Type2	163 - 474	S319D	None	5
3MTLA	2.4	Inactive	DFGout	None	in-in	out-none	FEF	Type1	163 - 473	S319D	None	12
5G6VB	2.2	Inactive	DFGout	None	in-in	out-out	919	Type2	163 - 475	S319D	None	12

CDK16 (Cyclin-dependent kinase 16)

Group: CMGC

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q00536-K1A
DFGout	BBAminus	1	5G6VA
DFGout	None	2	5G6VB

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	CDK16_HUMAN	AF-Q00536-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	157 - 454	None	None	0
Homo sapiens	CDK16_HUMAN	5G6VA	2.2	Inactive	DFGout	BBAminus	in-in	out-out	919	Type2	163 - 474	S319D	None	5
Homo sapiens	CDK16_HUMAN	3MTLA	2.4	Inactive	DFGout	None	in-in	out-none	FEF	Type1	163 - 473	S319D	None	12
Homo sapiens	CDK16_HUMAN	5G6VB	2.2	Inactive	DFGout	None	in-in	out-out	919	Type2	163 - 475	S319D	None	12

CDK16 (Cyclin-dependent kinase 16)

No non-human structures known.