PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 5X2AB
DFGin BLBplus 1 25.0% 5X2AD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5X2AD P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 4.5667 13.491 BLBplus -132.47, 164.02 73.22, 18.47 -66.23, 142.03 48.39, 91.71 77.4, 1.26 out-out out 13.9917 Saltbr-out 14.3497 HRD-in -72.94, -56.49 82.37, -10.91 out-out-out SNCooo out-out ActLoopNT-out 6.4634 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 3.06 APE9-dihe-in -69.62, 129.82 APE8-dihe-in -83.4, 65.28 APE8-rot-na 22.72 APE67-dihe-in -72.49, -3.02 -53.67, -40.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.8971 APE9-dist-out 8.2345 T790M,V948R None None XRAY 1.85 0.176 0.219 D 331.0 297.0 13 30 20 10 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AC P00533 700 1015 1210.0 7XO:1104 Type1 Inactive DFGin 5.5042 16.5389 BLBtrans -121.56, -177.75 69.47, 12.59 -60.5, 141.21 167.5, 68.5 89.76, -35.23 out-out out 13.5647 Saltbr-out 13.1372 HRD-in -66.9, -48.76 80.92, -13.83 out-out-out SNCooo out-out ActLoopNT-out 7.0213 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.32 APE8-dihe-in -80.48, 64.62 APE8-rot-na 38.22 APE67-dihe-in -72.09, -6.11 -53.33, -40.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.214 T790M,V948R None None XRAY 1.85 0.176 0.219 C 331.0 303.0 13 30 17 13 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AB P00533 700 1022 1210.0 7XO:1105,ANP:1106 Type1,ATPlike Inactive DFGin 5.521 16.3794 BLBtrans -118.08, 178.13 68.28, 22.21 -63.57, 132.1 161.37, 67.84 99.95, -15.3 out-out out 13.8924 Saltbr-out 13.5052 HRD-in -67.87, -49.57 81.65, -13.01 out-out-out SNCooo out-out ActLoopNT-out 6.3644 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -63.35, -22.61 APE9-dihe-in -95.03, 108.56 APE8-dihe-in -83.98, 72.85 APE8-rot-na 21.28 APE67-dihe-in -71.39, -9.89 -59.75, -39.3 APE12-dist-na 15.7264 APE11-dist-na 13.2452 APE10-dist-na 9.2736 APE9-dist-in 7.5679 T790M,V948R None None XRAY 1.85 0.176 0.219 B 331.0 322.0 0 30 30 0 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AA P00533 700 1011 1210.0 7XO:1107,ANP:1108 Type1,Allosteric Inactive DFGin 5.5648 16.303 BLBtrans -120.52, 179.71 70.51, 14.21 -61.87, 136.6 165.52, 70.66 90.66, -18.93 out-out out 13.7777 Saltbr-out 13.1042 HRD-in -79.48, -46.8 73.07, -8.08 out-out-none SNCoon out-none ActLoopNT-out 6.728 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 152.51 APE8-dihe-in -84.48, 76.35 APE8-rot-na 26.1 APE67-dihe-in -71.21, -12.48 -60.14, -38.61 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7618 T790M,V948R None None XRAY 1.85 0.176 0.219 A 331.0 297.0 13 30 17 13 [[712, 970]] 1.0 5x2a TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 5X2AB
DFGin BLBplus 1 25.0% 5X2AD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 5X2AD P00533 701 1014 1210.0 ANP:1102 ATPlike Inactive DFGin 4.5667 13.491 BLBplus -132.47, 164.02 73.22, 18.47 -66.23, 142.03 48.39, 91.71 77.4, 1.26 out-out out 13.9917 Saltbr-out 14.3497 HRD-in -72.94, -56.49 82.37, -10.91 out-out-out SNCooo out-out ActLoopNT-out 6.4634 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 3.06 APE9-dihe-in -69.62, 129.82 APE8-dihe-in -83.4, 65.28 APE8-rot-na 22.72 APE67-dihe-in -72.49, -3.02 -53.67, -40.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.8971 APE9-dist-out 8.2345 T790M,V948R None None XRAY 1.85 0.176 0.219 D 331.0 297.0 13 30 20 10 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AC P00533 700 1015 1210.0 7XO:1104 Type1 Inactive DFGin 5.5042 16.5389 BLBtrans -121.56, -177.75 69.47, 12.59 -60.5, 141.21 167.5, 68.5 89.76, -35.23 out-out out 13.5647 Saltbr-out 13.1372 HRD-in -66.9, -48.76 80.92, -13.83 out-out-out SNCooo out-out ActLoopNT-out 7.0213 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.32 APE8-dihe-in -80.48, 64.62 APE8-rot-na 38.22 APE67-dihe-in -72.09, -6.11 -53.33, -40.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.214 T790M,V948R None None XRAY 1.85 0.176 0.219 C 331.0 303.0 13 30 17 13 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AB P00533 700 1022 1210.0 7XO:1105,ANP:1106 Type1,ATPlike Inactive DFGin 5.521 16.3794 BLBtrans -118.08, 178.13 68.28, 22.21 -63.57, 132.1 161.37, 67.84 99.95, -15.3 out-out out 13.8924 Saltbr-out 13.5052 HRD-in -67.87, -49.57 81.65, -13.01 out-out-out SNCooo out-out ActLoopNT-out 6.3644 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -63.35, -22.61 APE9-dihe-in -95.03, 108.56 APE8-dihe-in -83.98, 72.85 APE8-rot-na 21.28 APE67-dihe-in -71.39, -9.89 -59.75, -39.3 APE12-dist-na 15.7264 APE11-dist-na 13.2452 APE10-dist-na 9.2736 APE9-dist-in 7.5679 T790M,V948R None None XRAY 1.85 0.176 0.219 B 331.0 322.0 0 30 30 0 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AA P00533 700 1011 1210.0 7XO:1107,ANP:1108 Type1,Allosteric Inactive DFGin 5.5648 16.303 BLBtrans -120.52, 179.71 70.51, 14.21 -61.87, 136.6 165.52, 70.66 90.66, -18.93 out-out out 13.7777 Saltbr-out 13.1042 HRD-in -79.48, -46.8 73.07, -8.08 out-out-none SNCoon out-none ActLoopNT-out 6.728 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 152.51 APE8-dihe-in -84.48, 76.35 APE8-rot-na 26.1 APE67-dihe-in -71.21, -12.48 -60.14, -38.61 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7618 T790M,V948R None None XRAY 1.85 0.176 0.219 A 331.0 297.0 13 30 17 13 [[712, 970]] 1.0 5x2a Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name