Ligand: ZL1

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 7MONA
DFGin BLBplus 1 50.0% 7MONB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER MLKL MLKL_HUMAN 7MONA Q8NB16 191 469 471.0 ZL1:501 Type1 Pseudo DFGin 9.979 16.865 BLAplus -145.54, -169.15 78.1, 22.67 -139.07, -9.53 71.34, 104.02 -105.01, 150.93 out-out out 16.381 Saltbr-out 13.326 HRD-na-E -68.26, -49.99 100.84, -31.32 out-out-out SNCooo out-out ActLoopNT-out 12.642 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -104.91, 135.41 APE9-dihe-na -71.07, 134.23 APE8-dihe-out -64.44, -25.38 APE8-rot-out 60.07 APE67-dihe-in -61.51, -31.54 -61.49, -26.48 APE12-dist-out 19.855 APE11-dist-out 24.032 APE10-dist-out 23.012 APE9-dist-out 13.36 None None None XRAY 2.23 0.212 0.26 A 287 268 11 0 0 8 [[204, 468]] 1.0 7mon OTHER_MLKL_HUMAN TKL 1.2e-50 178.4 7 266 260 348 349 350 352 354 230 250 254 328 330 329 331 394 380 375 374 373 372 371 370 369 284 Mixed lineage kinase domain-like protein
TKL RIPK3 RIPK3_HUMAN 7MONB Q9Y572 5 311 518.0 ZL1:401 Type1.5_Front Inactive DFGin 5.319 12.898 BLBplus -139.6, 164.18 56.61, 37.55 -80.29, 166.6 34.44, 92.89 79.72, -103.63 out-out out 11.648 Saltbr-out 7.413 HRD-in -76.18, -40.34 61.78, -4.08 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na 97.81, 14.44 APE9-dihe-na -63.58, 158.11 APE8-dihe-out -64.13, -29.56 APE8-rot-in 301.21 APE67-dihe-in -66.2, -17.44 -59.33, -40.24 APE12-dist-out 18.646 APE11-dist-out 21.316 APE10-dist-out 17.042 APE9-dist-out 10.554 C3S,C110A TPO224,SEP227 TPO224,SEP227 XRAY 2.23 0.212 0.26 B 316 285 22 0 0 12 [[21, 285]] 1.0 7mon TKL_RIPK3_HUMAN TKL 7.2e-66 228.4 1 265 265 159 160 161 163 165 50 60 64 139 141 140 142 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3

Ligand: ZL1

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 7MONA
DFGin BLBplus 1 50.0% 7MONB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER MLKL MLKL_HUMAN 7MONA Q8NB16 191 469 471.0 ZL1:501 Type1 Pseudo DFGin 9.979 16.865 BLAplus -145.54, -169.15 78.1, 22.67 -139.07, -9.53 71.34, 104.02 -105.01, 150.93 out-out out 16.381 Saltbr-out 13.326 HRD-na-E -68.26, -49.99 100.84, -31.32 out-out-out SNCooo out-out ActLoopNT-out 12.642 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -104.91, 135.41 APE9-dihe-na -71.07, 134.23 APE8-dihe-out -64.44, -25.38 APE8-rot-out 60.07 APE67-dihe-in -61.51, -31.54 -61.49, -26.48 APE12-dist-out 19.855 APE11-dist-out 24.032 APE10-dist-out 23.012 APE9-dist-out 13.36 None None None XRAY 2.23 0.212 0.26 A 287 268 11 0 0 8 [[204, 468]] 1.0 7mon Homo sapiens OTHER_MLKL_HUMAN TKL 1.2e-50 178.4 7 266 260 348 349 350 352 354 230 250 254 328 330 329 331 394 380 375 374 373 372 371 370 369 284 Mixed lineage kinase domain-like protein
TKL RIPK3 RIPK3_HUMAN 7MONB Q9Y572 5 311 518.0 ZL1:401 Type1.5_Front Inactive DFGin 5.319 12.898 BLBplus -139.6, 164.18 56.61, 37.55 -80.29, 166.6 34.44, 92.89 79.72, -103.63 out-out out 11.648 Saltbr-out 7.413 HRD-in -76.18, -40.34 61.78, -4.08 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na 97.81, 14.44 APE9-dihe-na -63.58, 158.11 APE8-dihe-out -64.13, -29.56 APE8-rot-in 301.21 APE67-dihe-in -66.2, -17.44 -59.33, -40.24 APE12-dist-out 18.646 APE11-dist-out 21.316 APE10-dist-out 17.042 APE9-dist-out 10.554 C3S,C110A TPO224,SEP227 TPO224,SEP227 XRAY 2.23 0.212 0.26 B 316 285 22 0 0 12 [[21, 285]] 1.0 7mon Homo sapiens TKL_RIPK3_HUMAN TKL 7.2e-66 228.4 1 265 265 159 160 161 163 165 50 60 64 139 141 140 142 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3

Ligand: ZL1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name