| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAplus | 5 | 4RZVB |
| DFGin | BLBminus | 1 | 2BTSA |
| DFGin | BLBplus | 1 | 3W32A |
| DFGin | None | 1 | 3PTGA |
| Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CMGC | CDK2 | CDK2_HUMAN | Cyclin-dependent kinase 2 | 2BTSA | 1.99 | Inactive | DFGin | BLBminus | out-out | none-out | U32 | Type1 |
| CMGC | MAPK10 | MK10_HUMAN | Mitogen-activated protein kinase 10 | 3PTGA | 2.43 | Inactive | DFGin | None | in-in | none-out | 932 | Type1 |
| TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | 4RZVA | 2.994 | Inactive | DFGin | BLAplus | out-out | out-out | 032 | Type1.5_Back |
| TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | 4RZVB | 2.994 | Inactive | DFGin | BLAplus | out-out | out-out | 032 | Type1.5_Back |
| TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | 3OG7A | 2.45 | Inactive | DFGin | BLAplus | out-out | none-out | 032 | Type1.5_Back |
| TKL | MAP3K20 | M3K20_HUMAN | Mitogen-activated protein kinase kinase kinase 20 | 5HESB | 2.14 | Inactive | DFGin | BLAplus | out-out | none-out | 032 | Type1 |
| TKL | MAP3K20 | M3K20_HUMAN | Mitogen-activated protein kinase kinase kinase 20 | 5HESA | 2.14 | Inactive | DFGin | BLAplus | out-out | out-out | 032 | Type1.5_Back |
| TYR | EGFR | EGFR_HUMAN | Epidermal growth factor receptor | 3W32A | 1.8 | Inactive | DFGin | BLBplus | out-out | out-in | W32 | Type1.5_Back |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | 2OXDA |
| DFGin | BLAplus | 5 | 4RZVB |
| DFGin | BLBminus | 1 | 2BTSA |
| DFGin | BLBplus | 1 | 3W32A |
| DFGin | None | 1 | 3PTGA |
| Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | CMGC | CDK2 | CDK2_HUMAN | Cyclin-dependent kinase 2 | 2BTSA | 1.99 | Inactive | DFGin | BLBminus | out-out | none-out | U32 | Type1 |
| Homo sapiens | CMGC | MAPK10 | MK10_HUMAN | Mitogen-activated protein kinase 10 | 3PTGA | 2.43 | Inactive | DFGin | None | in-in | none-out | 932 | Type1 |
| Homo sapiens | TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | 4RZVA | 2.994 | Inactive | DFGin | BLAplus | out-out | out-out | 032 | Type1.5_Back |
| Homo sapiens | TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | 4RZVB | 2.994 | Inactive | DFGin | BLAplus | out-out | out-out | 032 | Type1.5_Back |
| Homo sapiens | TKL | BRAF | BRAF_HUMAN | Serine/threonine-protein kinase B-raf | 3OG7A | 2.45 | Inactive | DFGin | BLAplus | out-out | none-out | 032 | Type1.5_Back |
| Homo sapiens | TKL | MAP3K20 | M3K20_HUMAN | Mitogen-activated protein kinase kinase kinase 20 | 5HESB | 2.14 | Inactive | DFGin | BLAplus | out-out | none-out | 032 | Type1 |
| Homo sapiens | TKL | MAP3K20 | M3K20_HUMAN | Mitogen-activated protein kinase kinase kinase 20 | 5HESA | 2.14 | Inactive | DFGin | BLAplus | out-out | out-out | 032 | Type1.5_Back |
| Homo sapiens | TYR | EGFR | EGFR_HUMAN | Epidermal growth factor receptor | 3W32A | 1.8 | Inactive | DFGin | BLBplus | out-out | out-in | W32 | Type1.5_Back |
| Zea mays | CMGC | ACK2 | CSK2A_MAIZE | Casein kinase II subunit alpha | 2OXDA | 2.3 | Active | DFGin | BLAminus | in-in | in-in | K32 | Type1 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | 2OXDA |