4CFE

PRKAA2 (5'-AMP-activated protein kinase catalytic subunit alpha-2)
Group: CAMK
Uniprot: AAPK2_HUMAN
Organism: Homo sapiens
Domain boundary: 16 - 268
Resolu: 3.023

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in STU 992 Type1 Allosteric 8 - 551 0
C Inactive DFGin BLAminus out-out in-in STU 992 Type1 Allosteric 10 - 551 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
         -          1         11         21 
mshhhhhhss glevlfqgpm aekqkhdgRV KIGHYVLGDT 
        31         41         51         61 
LGVGTFGKVK IGEHQLTGHK VAVKILNRQK IRSLDVVGKI 
        71         81         91        101 
KREIQNLKLF RHPHIIKLYQ VISTPTDFFM VMEYVSGGEL 
       111        121        131        141 
FDYICKHGRV EEMEARRLFQ QILSAVDYCH RHMVVHRDLK 
       151        161        171        181 
PENVLLDAHM NAKIADFGLS NMMSDGEFLR TSCGSPNYAA 
       191        201        211        221 
PEVISGRLYA GPEVDIWSCG VILYALLCGT LPFDDEHVPT 
       231        241        251        261 
LFKKIRGGVF YIPEYLNRSV ATLLMHMLQV DPLKRATIKD 
       271        281        291        301 
IREHEWFKQD LPSYLFPEDP SYDanvidde avkevcekfe 
       311        321        331        341 
ctesevmnsl ysgdpqdqla vayhlIIDNR RIMNQASEFY 
       351        361        371        381 
LASSPpsgsf mddsamhipp gLKPHPERMP PLiadspkar 
       391        401        411        421 
cpldalnttk pkslAVKKAK WHLGIRSQSK PYDIMAEVYR 
       431        441        451        461 
AMKQLDFEWK VVNAYHLRVR RKNPVTGNYV KMSLQLYLVD 
       471        481        491        501 
NRSYLLDFKS IDdevveqrs gsstpqrscs aaglhrprss 
       511        521        531        541 
fdsttaeshs lsgsltgslt gstlssvspr LGSHTMDFFE 
       551 
MCASLITTLA r
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X172