8BIK

PRKAA2 (5'-AMP-activated protein kinase catalytic subunit alpha-2)
Group: CAMK
Uniprot: AAPK2_HUMAN
Organism: Homo sapiens
Domain boundary: 16 - 268
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus out-in in-in STU QTN Type1 Allosteric 8 - 551 0
D Active DFGin BLAminus out-in in-in STU QTN Type1 Allosteric 9 - 551 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
         3         13         23         33 
mhhhhhhmae kqkhdGRVKI GHYVLGDTLG VGTFGKVKIG 
        43         53         63         73 
EHQLTGHKVA VKILNRQKIR SLDVVGKIKR EIQNLKLFRH 
        83         93        103        113 
PHIIKLYQVI STPTDFFMVM EYVSGGELFD YICKHGRVEE 
       123        133        143        153 
MEARRLFQQI LSAVDYCHRH MVVHRDLKPE NVLLDAHMNA 
       163        173        183        193 
KIADFGLSNM MSDGEFLRTS CGSPNYAAPE VISGRLYAGP 
       203        213        223        233 
EVDIWSCGVI LYALLCGTLP FDDEHVPTLF KKIRGGVFYI 
       243        253        263        273 
PEYLNRSVAT LLMHMLQVDP LKRATIKDIR EHEWFKQDLP 
       283        293        303        313 
SYLFPEDPSY DANVIDDEAV KEVCEKFECT ESEVMNSLYs 
       323        333        343        353 
gdPQDQLAVA YHLIIDNRRI MNQASEFYLA SSPpsgsfmd 
       363        373        383        393 
dsamhippgL KPHPERMPPL IAdspkarcp ldalnttkpk 
       403        413        423        433 
slavkKAKWH LGIRSQSKPY DIMAEVYRAM KQLDFEWKVV 
       443        453        463        473 
NAYHLRVRRK NPVTGNYVKM SLQLYLVDNR SYLLDFKSID 
       483        493        503        513 
devveqrsgs stpqrscsaa glhrprssfd sttaeshsls 
       523        533        543 
gsltgsltgs tlssvsprLG SHTMDFFEMC ASLITTLAr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None