OTHER_HASPIN (Serine/threonine-protein kinase haspin)

Total number of chains: 42
Active chains: 33
Uniprot: HASP_HUMAN
Kinase Domain Residues: 484 - 797
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 41 97.6% AF-Q8TF76-K1A
DFGin None 1 2.4% 9B2TK
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin
AF-Q8TF76-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin
AF-Q8TF76-K3A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin
2WB8A 2.15 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 447 - 798 0 None None Serine/threonine-protein kinase haspin
5HTBA 1.7 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin
5HTCA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin
6G39A 1.45 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605Y Serine/threonine-protein kinase haspin
2VUWA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
9FLTA 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDF Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
3E7VA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DZO Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
3F2NA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IZZ Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
3FMDA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IQB Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
3IQ7A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
4OUCA 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
4QTCA 1.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 38Z Type1 469 - 798 0 None None Serine/threonine-protein kinase haspin
6G34A 1.76 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin
6G35A 1.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKK Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin
6G36A 1.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKH Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin
6G37A 1.48 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa FTU Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin
6G38A 1.47 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBN Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin
6Z57A 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8W Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
6Z58A 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q9B Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
6Z59A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q98 Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
6Z5DA 1.75 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8Q Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
6Z5EA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8K Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
7AVQA 1.65 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa S1Z Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
7OPSA 2.38 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 07C Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
8RDKA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa YQT Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
9FLBA 2.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDB Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
9FLQA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDD Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
9FLRA 1.91 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDE Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin
7SQMA 1.78 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A5G Type1 453 - 798 0 None None Serine/threonine-protein kinase haspin
9FLCA 2.18 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDA Type1.5_Back 471 - 798 0 None None Serine/threonine-protein kinase haspin
9B2SK 3.01 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin
9B2UK 3.64 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin
6Z5CA 1.75 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa PQ5 Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin
9FLOA 2.9 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDC Type1 466 - 797 0 None None Serine/threonine-protein kinase haspin
6G3AA 1.43 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605T Serine/threonine-protein kinase haspin
6Z56A 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Q Type1.5_Back 470 - 798 0 None None Serine/threonine-protein kinase haspin
6Z5BA 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Z Type1.5_Back 469 - 798 0 None None Serine/threonine-protein kinase haspin
6Z5AA 1.55 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8B Type1.5_Front 465 - 798 0 None None Serine/threonine-protein kinase haspin
9B2TK 2.99 Inactive DFGin‑None out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin

OTHER_HASPIN (Serine/threonine-protein kinase haspin)

Total number of chains: 42
Active chains: 33
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 41 97.6% AF-Q8TF76-K1A
DFGin None 1 2.4% 9B2TK
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
HASP_HUMAN 3DLZA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa AMP ATPlike 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN AF-Q8TF76-K1A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN AF-Q8TF76-K3A -1.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 476 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 2WB8A 2.15 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 447 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 5HTBA 1.7 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 5HTCA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6G39A 1.45 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605Y Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 2VUWA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9FLTA 2.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDF Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 3E7VA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa DZO Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 3F2NA 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IZZ Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 3FMDA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa IQB Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 3IQ7A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 4OUCA 1.9 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 4QTCA 1.4 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 38Z Type1 469 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6G34A 1.76 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6G35A 1.55 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKK Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6G36A 1.46 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa EKH Type1 465 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6G37A 1.48 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa FTU Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6G38A 1.47 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa TBN Type1 472 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z57A 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8W Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z58A 1.8 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q9B Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z59A 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q98 Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z5DA 1.75 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8Q Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z5EA 1.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8K Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 7AVQA 1.65 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa S1Z Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 7OPSA 2.38 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa 07C Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 8RDKA 2.0 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa YQT Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9FLBA 2.5 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDB Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9FLQA 1.85 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDD Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9FLRA 1.91 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDE Type1 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 7SQMA 1.78 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A5G Type1 453 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9FLCA 2.18 Active DFGin‑BLAminus in-in in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDA Type1.5_Back 471 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9B2SK 3.01 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9B2UK 3.64 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z5CA 1.75 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa PQ5 Type1 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9FLOA 2.9 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa A1IDC Type1 466 - 797 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6G3AA 1.43 Inactive DFGin‑BLAminus in-out in-na noAPE APEdihe_aaaaa APEdist_aaaa 5ID Type1 471 - 798 0 None F605T Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z56A 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Q Type1.5_Back 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z5BA 1.9 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q7Z Type1.5_Back 469 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 6Z5AA 1.55 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8B Type1.5_Front 465 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens
HASP_HUMAN 9B2TK 2.99 Inactive DFGin‑None out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa No_ligand No_ligand 470 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens

OTHER_HASPIN (Serine/threonine-protein kinase haspin)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism