| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | ABAminus | in-out | in-in | H8H | Type1 | 205 - 499 | 3 |
| B | Inactive | DFGin | ABAminus | in-out | in-in | H8H | Type1 | 203 - 499 | 5 |
| C | Inactive | DFGin | ABAminus | in-none | in-in | H8H | Type1 | 201 - 498 | 2 |
| D | Inactive | DFGin | ABAminus | in-out | in-in | H8H | Type1 | 203 - 498 | 3 |
Representative sequence - Chain D
208 218 228 238
smqrTVARDI TLLECVGKgr YGEVWRGSWQ GENVAVKIFS
248 258 268 278
SRDEKSWFRE TELYNTVMLR HENILGFIAS DMTSRHSSTQ
288 298 308 318
LWLITHYHEM GSLYDYLQLT TLDTVSCLRI VLSIASGLAH
328 338 348 358
LHIEIFGTQG KPAIAHRDLK SKNILVKKNG QCCIADLGLA
368 378 388 398
VMHSQSTNQL DvgnNPRVGT KRYMAPEVLD ETIQVDCFDS
408 418 428 438
YKRVDIWAFG LVLWEVARRM VSNGIVEDYK PPFYDVVPND
448 458 468 478
PSFEDMRKVV CVDQQRPNIP NRWFSDPTLT SLAKLMKECW
488 498
YQNPSARLTA LRIKKTLTKI d