PDB: 9AXY — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9AXYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9AXYB Q02750 40 383 393.0 A1AHE:401,ANP:402 Type3,ATPlike Inactive DFGin 5.9383 14.1345 BLBplus -149.11, 165.49 51.9, 40.29 -92.3, 159.5 54.58, 76.32 -75.9, 70.87 out-out out 15.3992 Saltbr-out 14.9875 HRD-in -57.0, -47.47 79.88, -10.87 out-out-out SNCooo out-out ActLoopNT-out 9.3372 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -115.09, 128.49 APE9-dihe-na -79.18, 173.05 APE8-dihe-out -111.11, -19.81 APE8-rot-out 47.95 APE67-dihe-out -148.5, 141.81 -130.51, 175.5 APE12-dist-out 18.1758 APE11-dist-out 19.7311 APE10-dist-out 22.7854 APE9-dist-out 13.2287 S218A,S222A None None XRAY 3.6 0.19 0.237 B 394.0 312.0 32 26 26 0 [[68, 361]] 1.0 9axy STE_MAP2K1_HUMAN STE 1.1e-96 329.3 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 9AXYA P15056 448 722 766.0 ANP:801 ATPlike Inactive DFGin 5.9166 13.5406 BLBplus -133.51, 174.13 59.27, 33.71 -86.77, 154.56 49.71, 87.92 69.37, -142.48 out-out out 14.0958 Saltbr-out 13.0065 HRD-in -70.93, -41.64 75.57, -39.02 out-out-out SNCooo out-out ActLoopNT-out 9.0693 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -141.06, 145.96 APE9-dihe-na 71.75, -130.61 APE8-dihe-in -87.56, 149.58 APE8-rot-out 200.58 APE67-dihe-in -69.57, -29.74 -96.77, -9.15 APE12-dist-out 14.1942 APE11-dist-out 15.515 APE10-dist-out 11.6629 APE9-dist-out 9.6767 None None None XRAY 3.6 0.19 0.237 A 280.0 275.0 0 30 30 0 [[457, 716]] 1.0 9axy TKL_BRAF_HUMAN TKL 7.8e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 9AXY — 2 kinases

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 9AXYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K1 MP2K1_HUMAN 9AXYB Q02750 40 383 393.0 A1AHE:401,ANP:402 Type3,ATPlike Inactive DFGin 5.9383 14.1345 BLBplus -149.11, 165.49 51.9, 40.29 -92.3, 159.5 54.58, 76.32 -75.9, 70.87 out-out out 15.3992 Saltbr-out 14.9875 HRD-in -57.0, -47.47 79.88, -10.87 out-out-out SNCooo out-out ActLoopNT-out 9.3372 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -115.09, 128.49 APE9-dihe-na -79.18, 173.05 APE8-dihe-out -111.11, -19.81 APE8-rot-out 47.95 APE67-dihe-out -148.5, 141.81 -130.51, 175.5 APE12-dist-out 18.1758 APE11-dist-out 19.7311 APE10-dist-out 22.7854 APE9-dist-out 13.2287 S218A,S222A None None XRAY 3.6 0.19 0.237 B 394.0 312.0 32 26 26 0 [[68, 361]] 1.0 9axy Homo sapiens STE_MAP2K1_HUMAN STE 1.1e-96 329.3 1.0 257.0 257.0 207 208 209 211 213 97 114 118 187 189 188 190.0 245 233 228 227 226 225 224 223 222 144 Dual specificity mitogen-activated protein kinase kinase 1
TKL BRAF BRAF_HUMAN 9AXYA P15056 448 722 766.0 ANP:801 ATPlike Inactive DFGin 5.9166 13.5406 BLBplus -133.51, 174.13 59.27, 33.71 -86.77, 154.56 49.71, 87.92 69.37, -142.48 out-out out 14.0958 Saltbr-out 13.0065 HRD-in -70.93, -41.64 75.57, -39.02 out-out-out SNCooo out-out ActLoopNT-out 9.0693 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -141.06, 145.96 APE9-dihe-na 71.75, -130.61 APE8-dihe-in -87.56, 149.58 APE8-rot-out 200.58 APE67-dihe-in -69.57, -29.74 -96.77, -9.15 APE12-dist-out 14.1942 APE11-dist-out 15.515 APE10-dist-out 11.6629 APE9-dist-out 9.6767 None None None XRAY 3.6 0.19 0.237 A 280.0 275.0 0 30 30 0 [[457, 716]] 1.0 9axy Homo sapiens TKL_BRAF_HUMAN TKL 7.8e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 9AXY — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name